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N-[(1,2-二氢-6-甲基-2-氧代-4-丙基-3-吡啶基)甲基]-1-(1-甲基乙基)-6-[6-[4-(1-甲基乙基)-1-哌嗪基]-3-吡啶基]-1H-吲唑-4-甲酰胺

N-[(1,2-二氢-6-甲基-2-氧代-4-丙基-3-吡啶基)甲基]-1-(1-甲基乙基)-6-[6-[4-(1-甲基乙基)-1-哌嗪基]-3-吡啶基]-1H-吲唑-4-甲酰胺结构式
N-[(1,2-二氢-6-甲基-2-氧代-4-丙基-3-吡啶基)甲基]-1-(1-甲基乙基)-6-[6-[4-(1-甲基乙基)-1-哌嗪基]-3-吡啶基]-1H-吲唑-4-甲酰胺结构式
品牌特惠专场
常用名 N-[(1,2-二氢-6-甲基-2-氧代-4-丙基-3-吡啶基)甲基]-1-(1-甲基乙基)-6-[6-[4-(1-甲基乙基)-1-哌嗪基]-3-吡啶基]-1H-吲唑-4-甲酰胺 英文名 UNC1999
CAS号 1431612-23-5 分子量 569.740
密度 1.2±0.1 g/cm3 沸点 804.7±65.0 °C at 760 mmHg
分子式 C33H43N7O2 熔点 N/A
MSDS 中文版 美版 闪点 440.4±34.3 °C
符号 GHS07
GHS07
信号词 Warning

EZH2 inhibition enhances the efficacy of an EGFR inhibitor in suppressing colon cancer cells.

Cancer Biol. Ther. 15(12) , 1677-87, (2014)

Metastatic colon cancer has a 5-year survival of less than 10% despite the use of aggressive chemotherapeutic regimens. As signaling from epidermal growth factor receptor (EGFR) is often enhanced and epigenetic regulation is often altered in colon cancer, it ...