UNC1999

UNC1999 Structure
UNC1999 structure
Common Name UNC1999
CAS Number 1431612-23-5 Molecular Weight 569.740
Density 1.2±0.1 g/cm3 Boiling Point 804.7±65.0 °C at 760 mmHg
Molecular Formula C33H43N7O2 Melting Point N/A
MSDS Chinese USA Flash Point 440.4±34.3 °C
Symbol GHS07
GHS07
Signal Word Warning

EZH2 inhibition enhances the efficacy of an EGFR inhibitor in suppressing colon cancer cells.

Cancer Biol. Ther. 15(12) , 1677-87, (2014)

Metastatic colon cancer has a 5-year survival of less than 10% despite the use of aggressive chemotherapeutic regimens. As signaling from epidermal growth factor receptor (EGFR) is often enhanced and epigenetic regulation is often altered in colon cancer, it ...