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KH7

KH7结构式
KH7结构式
品牌特惠专场
常用名 KH7 英文名 KH 7
CAS号 330676-02-3 分子量 419.296
密度 1.6±0.1 g/cm3 沸点 N/A
分子式 C17H15BrN4O2S 熔点 N/A
MSDS 美版 闪点 N/A
符号 GHS06
GHS06
信号词 Danger

Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages.

J. Immunol. 194 , 5472-87, (2015)

PGE2 is a potent lipid mediator involved in maintaining homeostasis but also promotion of acute inflammation or immune suppression in chronic inflammation and cancer. Nucleotide-binding domain, leucine-rich repeat-containing protein (NLR)P3 inflammasome plays...

Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration.

J. Exp. Med. 212 , 1021-41, (2015)

CD99 is a critical regulator of leukocyte transendothelial migration (TEM). How CD99 signals during this process remains unknown. We show that during TEM, endothelial cell (EC) CD99 activates protein kinase A (PKA) via a signaling complex formed with the lysi...

Short- and long-term regulation of intestinal Na+/H+ exchange by Toll-like receptors TLR4 and TLR5.

Am. J. Physiol. Gastrointest. Liver Physiol. 309 , G703-15, (2015)

Inappropriate activation of pattern recognition receptors has been described as a potential trigger in the development of inflammatory bowel disease (IBD). In this study, we evaluated the activity and expression of Na(+)/H(+) exchanger (NHE) subtypes in T84 i...

Resveratrol improves hepatic steatosis by inducing autophagy through the cAMP signaling pathway.

Mol. Nutr. Food. Res. 59 , 1443-57, (2015)

Resveratrol (RSV), a natural polyphenol, has been reported to attenuate nonalcoholic fatty liver disease (NAFLD); however, its underlying mechanism is unclear. Autophagy was recently identified as a critical protective mechanism during NAFLD development. Ther...

Alcohol Decreases Organic Dust-Stimulated Airway Epithelial TNF-Alpha Through a Nitric Oxide and Protein Kinase-Mediated Inhibition of TACE.

Alcohol. Clin. Exp. Res. 40 , 273-83, (2016)

Farm workers in rural areas consume more alcohol than those who reside in urban areas. Occupational exposures such as agricultural work can pose hazards on the respiratory system. It is established that hog barn dust induces inflammation in the airway, includ...