PhTX-433
PhTX-433结构式
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常用名 | PhTX-433 | 英文名 | PhTX-433 |
|---|---|---|---|---|
| CAS号 | 276684-27-6 | 分子量 | 777.67300 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C29H44F9N5O9 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A | |
| 符号 |
GHS06 |
信号词 | Danger |
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Effects of philanthotoxin-343 on CA1 pyramidal neurons of rat hippocampus in vitro.
Eur. J. Pharmacol. 228 , 201-206, (1992) A synthetic analog of philanthotoxin-433, philanthotoxin-343 (PhTX-343), was tested in hippocampal pyramidal neurons in vitro. PhTX-343 (2 microM) did not significantly change synaptic transmission mediated by AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole ... |
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Philanthotoxin inhibits Ca2+ currents in rat hippocampal CA1 neurons.
Eur. J. Pharmacol. 270 , 357-360, (1994) The wasp venom philanthotoxin-4.3.3 (PhTX-4.3.3) is an antagonist of glutamate transmission in the insect as well as in the mammalian brain. It was recently shown that PhTX-4.3.3 inhibits the N-methyl-D-aspartate (NMDA) transmission in rat hippocampus. In thi... |
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Inhibition of dipteran larval neuromuscular synaptic transmission by analogues of philanthotoxin-4.3.3: a structure-activity study.
Comp. Biochem. Physiol. 102C , 267-272, (1992) 1. The blocking action of delta-philanthotoxin (PhTX-4.3.3), a wasp toxin composed of a polyamine chain, an aromatic amino acid (tyrosyl) nucleus and an aliphatic (butanoic) acid was studied, together with 33 structural analogues, at the glutamatergic neuromu... |
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Selective antagonism of native and cloned kainate and NMDA receptors by polyamine-containing toxins.
J. Pharmacol. Exp. Ther. 266 , 1573-1580, (1993) Antagonism of rat excitatory amino acid receptors by a synthetic analog [philanthotoxin-343 (PhTX-343)] of a polyamine amide, wasp toxin (philanthotoxin-433) and a structurally related spider toxin, argiotoxin-636 (ArgTX-636), was examined in Xenopus oocytes ... |