普瑞巴林
普瑞巴林结构式
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常用名 | 普瑞巴林 | 英文名 | Pregabalin |
|---|---|---|---|---|
| CAS号 | 148553-50-8 | 分子量 | 159.226 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 274.0±23.0 °C at 760 mmHg | |
| 分子式 | C8H17NO2 | 熔点 | 194-196ºC | |
| MSDS | 中文版 美版 | 闪点 | 119.5±22.6 °C | |
| 符号 |
GHS05, GHS08 |
信号词 | Danger |
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Development of a SPE-HPLC-MS/MS method for the determination of most prescribed pharmaceuticals and related metabolites in urban sewage samples.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 990 , 23-30, (2015) Based on regional prescription data several pharmaceuticals with variable amounts of prescription and corresponding metabolites were selected and analyzed in influent and effluent samples of the sewage treatment plant (STP) in Dresden, Germany. Pharmaceutical... |
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Effect of the gastrointestinal prokinetic agent erythromycin on the pharmacokinetics of pregabalin controlled-release in healthy individuals: a phase I, randomized crossover trial.
Clin. Drug Investig. 35(5) , 299-305, (2015) The controlled-release (CR) formulation of pregabalin is designed to remain in the stomach for a prolonged period while slowly releasing pregabalin for absorption in the small intestine. This study evaluated the effect of the gastrointestinal prokinetic agent... |
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Evaluation of the matrix effect of different sample matrices for 33 pharmaceuticals by post-column infusion.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 1000 , 84-94, (2015) Matrix effects that occur during quantitative measurement by liquid chromatography mass spectrometry specifically when using electrospray ionization are a widely recognized phenomenon. Sample matrix compounds affect the ionization process of the target analyt... |
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Clinical study evaluating pregabalin efficacy and tolerability for pain management in patients undergoing laparoscopic cholecystectomy.
Clin. J. Pain 30(11) , 944-52, (2014) To evaluate the efficacy and tolerability of pregabalin in postoperative pain management after laparoscopic cholecystectomy (LC).A prospective, randomized, placebo, controlled, double-blinded study was conducted at Anesthesia Department, Laparoscopy Surgery U... |
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Comparison of central versus peripheral delivery of pregabalin in neuropathic pain states.
Mol. Pain 8 , 3, (2012) Although pregabalin therapy is beneficial for neuropathic pain (NeP) by targeting the CaVα2δ-1 subunit, its site of action is uncertain. Direct targeting of the central nervous system may be beneficial for the avoidance of systemic side effects.We used intran... |