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2-金刚烷胺盐酸

2-金刚烷胺盐酸结构式
2-金刚烷胺盐酸结构式
品牌特惠专场
常用名 2-金刚烷胺盐酸 英文名 2-adamantaneamine hydrochloride
CAS号 10523-68-9 分子量 187.710
密度 N/A 沸点 226.1ºC at 760 mmHg
分子式 C10H18ClN 熔点 >300 °C(lit.)
MSDS 中文版 美版 闪点 96.5ºC
符号 GHS07
GHS07
信号词 Warning

Modification of the antibiotic olivomycin I at the 2'-keto group of the side chain. Novel derivatives, antitumor and topoisomerase I-poisoning activity.

J. Antibiot. 62(1) , 37-41, (2009)

A novel way of chemical modification of the antibiotic olivomycin I at the 2'-keto group of the side chain of the aglycone moiety was developed. Reaction of olivomycin I with the carboxymethoxylamine hemihydrochloride gave the key intermediate, 2'-carboxymeth...

Simultaneous liquid chromatographic assay of amantadine and its four related compounds in phosphate-buffered saline using 4-fluoro-7-nitro-2,1,3-benzoxadiazole as a fluorescent derivatization reagent.

Biomed. Chromatogr. 20(5) , 423-8, (2006)

Simultaneous HPLC assay of 1-adamantanamine hydrochloride (amantadine) and its four related compounds [2-adamantanamine hydrochloride (2-ADA), 1-adamantanmethylamine (ADAMA), 1-(1-adamantyl)ethylamine hydrochloride (rimantadine) and 3,5-dimethyl-1-adamantanam...

[A quantitative pharmaco-electroencephalographic analysis of the action of bromantane].

Biull. Eksp. Biol. Med. 116(11) , 515-8, (1993)

The action of the new stimulant bromantane on spectra power EEG on Fourier of sensorimotor cortex, dorsal hippocamp and lateral hypothalamus of left and right hemispheres of brain of rat in free behavior was investigated. Bromantane leads to decreases in the ...

[DNA macroarray analysis of gene expression changes in rat brain after single administration of 2-aminoadamantane compound].

Mol. Biol. (Mosk.) 39(2) , 276-85, (2005)

We have used the Rat Atlas cDNA Array ("BD Bioscience") to assess changes in mRNA expression of 588 genes in rat brain after acute treatment of 2-aminoadamantane compound--Ladasten. Drug exhibits the psychostimulating and anxyolitic actions. The analysis of r...

Inhibition of lymphocyte proliferation by amantadine and its isomer, 2-aminoadamantane; impact on Lyt-2+ T cells while sparing L3T4+ T cells.

Immunopharmacology 21(1) , 41-50, (1991)

The present in vitro investigations on amantadine (AmTd) and its isomer 2-aminoadamantane (2-NH2-Adam), and the corresponding analogs, 1-nitroadamantane (1-NO2-Adam) and 2-nitroadamantane (2-NO2-Adam), were undertaken to gain information about molecular featu...