2-adamantaneamine hydrochloride
2-adamantaneamine hydrochloride structure
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Common Name | 2-adamantaneamine hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 10523-68-9 | Molecular Weight | 187.710 | |
| Density | N/A | Boiling Point | 226.1ºC at 760 mmHg | |
| Molecular Formula | C10H18ClN | Melting Point | >300 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 96.5ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Modification of the antibiotic olivomycin I at the 2'-keto group of the side chain. Novel derivatives, antitumor and topoisomerase I-poisoning activity.
J. Antibiot. 62(1) , 37-41, (2009) A novel way of chemical modification of the antibiotic olivomycin I at the 2'-keto group of the side chain of the aglycone moiety was developed. Reaction of olivomycin I with the carboxymethoxylamine hemihydrochloride gave the key intermediate, 2'-carboxymeth... |
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Simultaneous liquid chromatographic assay of amantadine and its four related compounds in phosphate-buffered saline using 4-fluoro-7-nitro-2,1,3-benzoxadiazole as a fluorescent derivatization reagent.
Biomed. Chromatogr. 20(5) , 423-8, (2006) Simultaneous HPLC assay of 1-adamantanamine hydrochloride (amantadine) and its four related compounds [2-adamantanamine hydrochloride (2-ADA), 1-adamantanmethylamine (ADAMA), 1-(1-adamantyl)ethylamine hydrochloride (rimantadine) and 3,5-dimethyl-1-adamantanam... |
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[A quantitative pharmaco-electroencephalographic analysis of the action of bromantane].
Biull. Eksp. Biol. Med. 116(11) , 515-8, (1993) The action of the new stimulant bromantane on spectra power EEG on Fourier of sensorimotor cortex, dorsal hippocamp and lateral hypothalamus of left and right hemispheres of brain of rat in free behavior was investigated. Bromantane leads to decreases in the ... |
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[DNA macroarray analysis of gene expression changes in rat brain after single administration of 2-aminoadamantane compound].
Mol. Biol. (Mosk.) 39(2) , 276-85, (2005) We have used the Rat Atlas cDNA Array ("BD Bioscience") to assess changes in mRNA expression of 588 genes in rat brain after acute treatment of 2-aminoadamantane compound--Ladasten. Drug exhibits the psychostimulating and anxyolitic actions. The analysis of r... |
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Inhibition of lymphocyte proliferation by amantadine and its isomer, 2-aminoadamantane; impact on Lyt-2+ T cells while sparing L3T4+ T cells.
Immunopharmacology 21(1) , 41-50, (1991) The present in vitro investigations on amantadine (AmTd) and its isomer 2-aminoadamantane (2-NH2-Adam), and the corresponding analogs, 1-nitroadamantane (1-NO2-Adam) and 2-nitroadamantane (2-NO2-Adam), were undertaken to gain information about molecular featu... |