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5-溴-2-氟苯腈

5-溴-2-氟苯腈结构式
5-溴-2-氟苯腈结构式
品牌特惠专场
常用名 5-溴-2-氟苯腈 英文名 5-Bromo-2-fluorobenzonitrile
CAS号 179897-89-3 分子量 200.008
密度 1.7±0.1 g/cm3 沸点 220.4±20.0 °C at 760 mmHg
分子式 C7H3BrFN 熔点 76-81 °C
MSDS 中文版 美版 闪点 87.1±21.8 °C
符号 GHS07
GHS07
信号词 Warning

Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors.

Bioorg. Med. Chem. 14(20) , 6832-46, (2006)

A series of heteroaryl-pyridine containing inhibitors of Akt are reported. The synthesis and structure-activity relationships are discussed, leading to the discovery of a indazole-pyridine analogue (K(i)=0.16 nM). These compounds bind in the ATP binding site,...

Synthesis of structurally identical fluorine-18 and iodine isotope labeling compounds for comparative imaging.

Bioconjug. Chem. 14(2) , 287-94, (2003)

The synthesis of a benzophenone-based labeling compound designed for comparative imaging studies with both in vivo positron emission tomograph (PET) and single-photon computed tomography (SPECT) and ex vivo autoradiography is described. The new compound can b...

Microwave-assisted synthesis of 3-aminobenzo [b] thiophene scaffolds for the preparation of kinase inhibitors. Bagley MC, et al.

Org. Biomol. Chem. , (2015)