5-Bromo-2-fluorobenzonitrile

5-Bromo-2-fluorobenzonitrile Structure
5-Bromo-2-fluorobenzonitrile structure
Common Name 5-Bromo-2-fluorobenzonitrile
CAS Number 179897-89-3 Molecular Weight 200.008
Density 1.7±0.1 g/cm3 Boiling Point 220.4±20.0 °C at 760 mmHg
Molecular Formula C7H3BrFN Melting Point 76-81 °C
MSDS Chinese USA Flash Point 87.1±21.8 °C
Symbol GHS07
GHS07
Signal Word Warning

Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors.

Bioorg. Med. Chem. 14(20) , 6832-46, (2006)

A series of heteroaryl-pyridine containing inhibitors of Akt are reported. The synthesis and structure-activity relationships are discussed, leading to the discovery of a indazole-pyridine analogue (K(i)=0.16 nM). These compounds bind in the ATP binding site,...

Synthesis of structurally identical fluorine-18 and iodine isotope labeling compounds for comparative imaging.

Bioconjug. Chem. 14(2) , 287-94, (2003)

The synthesis of a benzophenone-based labeling compound designed for comparative imaging studies with both in vivo positron emission tomograph (PET) and single-photon computed tomography (SPECT) and ex vivo autoradiography is described. The new compound can b...

Microwave-assisted synthesis of 3-aminobenzo [b] thiophene scaffolds for the preparation of kinase inhibitors. Bagley MC, et al.

Org. Biomol. Chem. , (2015)