四氯化硒
一般危化品
四氯化硒结构式
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常用名 | 四氯化硒 | 英文名 | Selenium(IV) chloride (-8 mesh) |
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| CAS号 | 10026-03-6 | 分子量 | 220.77200 | |
| 密度 | 2.6 g/mL at 25 °C(lit.) | 沸点 | 288ºC | |
| 分子式 | Cl4Se | 熔点 | 200-210ºC | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS06, GHS08, GHS09 |
信号词 | Danger |
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Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep.
Proc. Natl. Acad. Sci. U. S. A. 103(47) , 17949-54, (2006) Prostaglandin (PG) D2 has been proposed to be essential for the initiation and maintenance of the physiological sleep of rats because intracerebroventricular administration of selenium tetrachloride (SeCl4), a selective inhibitor of PGD synthase (PGDS), was s... |
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Prostaglandin D synthase in the prenatal ovine brain and effects of its inhibition with selenium chloride on fetal sleep/wake activity in utero.
J. Neurosci. 22(13) , 5679-86, (2002) It has been proposed that prostaglandin (PG) D(2) induces physiological sleep in mammals by acting on sleep centers located in the anterior hypothalamus. In fetal sheep, definitive rapid-eye-movement and non-rapid-eye-movement sleep states appear at approxima... |
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Inhibition of sleep in rats by inorganic selenium compounds, inhibitors of prostaglandin D synthase.
Proc. Natl. Acad. Sci. U. S. A. 88(20) , 9046-50, (1991) Prostaglandin (PG) D2 has been postulated to be an endogenous sleep-promoting factor in rats, and SeCl4 and Na2SeO3 recently have been shown to inhibit the PGD synthase (prostaglandin-H2 D-isomerase, EC 5.3.99.2) activity of rat brain. The effect of these sel... |
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Inhibition of rat brain prostaglandin D synthase by inorganic selenocompounds.
Arch. Biochem. Biophys. 289(1) , 161-6, (1991) Various inorganic selenocompounds dose-dependently inhibited the rat brain prostaglandin (PG) D synthase, both in the purified enzyme preparation and in the crude brain supernatant. All of the quadrivalent selenium compounds tested had a very limited range of... |
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Retrograde tracing of zinc-containing neurons by selenide ions: a survey of seven selenium compounds.
J. Histochem. Cytochem. 40(4) , 575-9, (1992) The autometallographic retrograde tracing of zinc-containing neurons by intracerebral injection of sodium selenite (Na2SeO3), introduced by Danscher in 1982, has recently been described in more detail. Intracerebral injections of both sodium selenide (Na2Se) ... |
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Intravenous administration of inorganic selenium compounds, inhibitors of prostaglandin D synthase, inhibits sleep in freely moving rats.
Brain Res. 623(1) , 65-71, (1993) Prostaglandin (PG) D2 has been postulated to be an endogenous sleep-promoting factor. Biosynthesis of PGD2 is catalyzed by PGD synthase (prostaglandin-H2 D-isomerase, EC 5.3.99.2), the activity of which is inhibited by inorganic selenium compounds such as SeC... |
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5-Selenization of salicylic acid derivatives yielded isoform-specific 5-lipoxygenase inhibitors.
Org. Biomol. Chem. 8(4) , 828-34, (2010) Low molecular weight seleno-organic compounds exhibit glutathione peroxidase (GPx)-like activity; the well-known compound ebselen is being used in clinical trials as a stroke medication. Here, we describe the facile one-step synthesis of novel 5-selenized sal... |