β-鹅膏菌素
β-鹅膏菌素结构式
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常用名 | β-鹅膏菌素 | 英文名 | beta-Amanitin |
|---|---|---|---|---|
| CAS号 | 21150-22-1 | 分子量 | 919.95400 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C39H53N9O15S | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS06 |
信号词 | Danger |
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[Determination of amanitatoxins by HPLC].
Chudoku. Kenkyu. 16(4) , 441-5, (2003) High-performance liquid chromatographic (HPLC) assay has been developed for the simultaneous determination of alpha-amanitin, beta-amanitin and phalloidin in serum. Three toxins were extracted by reflux in a water bath at 80 degrees C for one hour and purifie... |
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Gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS) in toxicological analysis. Studies on the detection of clobenzorex and its metabolites within a systematic toxicological analysis procedure by GC-MS and by immunoassay and studies on the detection of alpha- and beta-amanitin in urine by atmospheric pressure ionization electrospray LC-MS.
J. Chromatogr. B. Biomed. Sci. Appl. 689(1) , 81-9, (1997) GC-MS is the method of choice for toxicological analysis of toxicants volatile in GC while non-volatile and/or thermally labile toxicants need LC-MS for their determination. Studies are presented on the toxicological detection of the amphetamine-like anorecti... |
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Validated electrospray liquid chromatographic-mass spectrometric assay for the determination of the mushroom toxins alpha- and beta-amanitin in urine after immunoaffinity extraction.
J. Chromatogr. B. Biomed. Sci. Appl. 748(1) , 125-35, (2000) Specific detection of amanitins in body fluids is necessary for an early diagnosis of an intoxication with amanita mushrooms. In this paper, a liquid chromatographic-mass spectrometric assay after immunoaffinity extraction (IAE-LC-MS) is described for the det... |
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Determination of alpha-amanitin and beta-amanitin in human biological fluids by high-performance liquid chromatography.
Anal. Biochem. 149(1) , 35-42, (1985) A high-performance liquid chromatographic assay of alpha-amanitin and beta-amanitin in human serum, urine, or stomach washings is described. Sample preparation involves a chemical step with deproteinization and organic solvent treatment, and a selective clean... |
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Strongly enhanced toxicity of the mushroom toxin alpha-amanitin by an amatoxin-specific Fab or monoclonal antibody.
Toxicon 26(5) , 491-9, (1988) A monoclonal antibody, with high affinity against the mushroom toxin alpha-amanitin, was prepared. Administration of the Fab fragment of the monoclonal antibody to mice caused a 50-fold increase in alpha-amanitin toxicity. Electron micrographs showed normal a... |
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Determination of alpha- and beta-amanitin in clinical urine samples by Capillary Zone Electrophoresis.
J. Pharm. Biomed. Anal. 47(4-5) , 913-7, (2008) Amanitins are toxins found in species of the mushroom genera Amanita, Lepiota and Galerina. Intoxication after ingestion of these mushrooms can be fatal with an estimated 20% of mortality rate. An early diagnosis is necessary in order to avoid invasive and ex... |
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A highly sensitive and specific enzyme immunoassay for detection of beta-amanitin in biological fluids.
Anal. Bioanal. Chem 379(5-6) , 853-60, (2004) Polyclonal antisera to beta-amanitin were generated in sheep and used to construct a competitive ELISA for measurement of the toxin in human serum and urine. The assay had a detection limit of about 80 pg mL(-1), a dynamic range of 80-2,000 pg mL(-1), a cross... |
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Illumina-based de novo transcriptome sequencing and analysis of Amanita exitialis basidiocarps.
Gene 532(1) , 63-71, (2013) Amanita exitialis is a lethal mushroom that was first discovered in Guangdong Province, China. The high content of amanitin in its basidiocarps makes it lethal to humans. To comprehensively characterize the A. exitialis transcriptome and analyze the Amanita t... |
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Preparation of a beta-amanitin-concanavalin A conjugate of low toxicity.
Toxicon 25(9) , 981-7, (1987) Pure beta-amanitin was isolated by combined adsorption chromatography of a crude methanol extract from Amanita phalloides on Sephasorb HP Ultrafine and Sephadex LH-20. The beta-amanitin was coupled to concanavalin A by the carbodiimide method. The conjugate w... |
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Gene activity during germination of spores of the fern, Onoclea sensibilis. Cell-free translation analysis of mRNA of spores and the effect of alpha-amanitin on spore germination.
J. Plant Physiol. 140(4) , 434-40, (1992) Poly(A)-RNA fractions of dormant, dark-imbibed (non-germinating) and photoinduced (germinating) spores of Onoclea sensibilis were poor templates in the rabbit reticulocyte lysate protein synthesizing system, but the translational efficiency of poly(A)+RNA was... |