环状ADP核糖
环状ADP核糖结构式
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常用名 | 环状ADP核糖 | 英文名 | Cyclic ADP-ribose |
|---|---|---|---|---|
| CAS号 | 119340-53-3 | 分子量 | 541.30000 | |
| 密度 | 2.57 g/cm3 | 沸点 | 934.8ºC at 760 mmHg | |
| 分子式 | C15H21N5O13P2 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 519.1ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Cyclic ADP-ribose requires CD38 to regulate the release of ATP in visceral smooth muscle.
FEBS J. 278 , 3095-3108, (2011) It is well established that the intracellular second messenger cADP-ribose (cADPR) activates Ca(2+) release from the sarcoplasmic reticulum through ryanodine receptors. CD38 is a multifunctional enzyme involved in the formation of cADPR in mammals. CD38 has a... |
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β-Adrenergic receptor signaling increases NAADP and cADPR levels in the heart.
Biochem. Biophys. Res. Commun. 427(2) , 326-9, (2012) Evidence suggests that β-Adrenergic receptor signaling increases heart rate and force through not just cyclic AMP but also the Ca(2+)-releasing second messengers NAADP (nicotinic acid adenine dinucleotide phosphate) and cADPR (cyclic ADP-ribose). Nevertheless... |
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Pyridine nucleotide metabolites and calcium release from intracellular stores.
Adv. Exp. Med. Biol. 740 , 305-23, (2012) Ca(2+) signals are probably the most common intracellular signaling elements, controlling an extensive range of responses in virtually all cells. Many cellular stimuli, often acting at cell surface receptors, evoke Ca(2+) signals by mobilizing Ca(2+) from int... |
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Fertilization in echinoderms.
Biochem. Biophys. Res. Commun. 425(3) , 588-94, (2012) For more than 150 years, echinoderm eggs have served as overly favored experimental model systems in which to study fertilization. Sea urchin and starfish belong to the same phylum and thus share many similarities in their fertilization patterns. However, sev... |
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Calcium pathway machinery at fertilization in echinoderms.
Cell Calcium 53(1) , 16-23, (2013) Calcium signaling in cells directs diverse physiological processes. The calcium waves triggered by fertilization is a highly conserved calcium signaling event essential for egg activation, and has been documented in every egg tested. This activity is one of t... |
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Roles of cADPR and NAADP in pancreatic cells.
Acta Biochim. Biophys. Sin. (Shanghai) 44(9) , 719-29, (2012) Cyclic ADP-ribose (cADPR) and nicotinic acid adenine dinucleotide phosphate (NAADP) are Ca(2+)-mobilizing nucleotides that were discovered in the late 1980s. Two decades of investigations have built up a considerable understanding about these two molecules th... |
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Cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate (NAADP) as messengers for calcium mobilization.
J. Biol. Chem. 287(38) , 31633-40, (2012) Cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate were discovered >2 decades ago. That they are second messengers for mobilizing Ca(2+) stores has since been firmly established. Separate stores and distinct Ca(2+) channels are targeted, with... |
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Regulation of ion channels by pyridine nucleotides.
Circ. Res. 112(4) , 721-41, (2013) Recent research suggests that in addition to their role as soluble electron carriers, pyridine nucleotides [NAD(P)(H)] also regulate ion transport mechanisms. This mode of regulation seems to have been conserved through evolution. Several bacterial ion-transp... |
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MicroR828 regulates lignin and H2O2 accumulation in sweet potato on wounding.
New Phytol. 196(2) , 427-40, (2012) MicroRNAs (miRNAs) are small noncoding RNAs which post-transcriptionally regulate gene expression by directing mRNA cleavage or translational inhibition. miRNAs play multiple roles in the growth, development and stress responses in plants. However, little is ... |
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The role of dietary niacin intake and the adenosine-5'-diphosphate-ribosyl cyclase enzyme CD38 in spatial learning ability: is cyclic adenosine diphosphate ribose the link between diet and behaviour?
Nutr. Res. Rev. 21(1) , 42-55, (2008) The pyridine nucleotide NAD+ is derived from dietary niacin and serves as the substrate for the synthesis of cyclic ADP-ribose (cADPR), an intracellular Ca signalling molecule that plays an important role in synaptic plasticity in the hippocampus, a region of... |