2-环戊烯酮
2-环戊烯酮结构式
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常用名 | 2-环戊烯酮 | 英文名 | Cyclopentenone |
|---|---|---|---|---|
| CAS号 | 930-30-3 | 分子量 | 82.10 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 136.0±0.0 °C at 760 mmHg | |
| 分子式 | C5H6O | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 42.2±0.0 °C | |
| 符号 |
GHS02 |
信号词 | Warning |
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The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes.
J. Immunol. 194(6) , 2776-85, (2015) Inflammasomes are cytosolic protein complexes that respond to diverse danger signals by activating caspase-1. The sensor components of the inflammasome, often proteins of the nucleotide-binding oligomerization domain-like receptor (NLR) family, detect stress,... |
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Enantioselective synthesis of 4-heterosubstituted cyclopentenones.
J. Org. Chem. 78(8) , 4202-6, (2013) Racemic 4-hydroxycyclopentenone, readily derived from furfuryl alcohol, can be transformed via its O-Boc derivative to 4-acyloxy, 4-aryloxy-, 4-amino-, or 4-thio-substituted cyclopentenones with high enantioselectivity by palladium-catalyzed kinetic resolutio... |
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Sinularones A-I, new cyclopentenone and butenolide derivatives from a marine soft coral Sinularia sp. and their antifouling activity.
Mar. Drugs 10(6) , 1331-44, (2012) Nine new compounds, namely sinularones A-I (1-9), characterized as cyclopentenone and butenolide-type analogues, were isolated from a soft coral Sinularia sp., together with a known butenolide (10). Their structures were elucidated by means of spectroscopic (... |
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Regioselective cleavage of 22-oxo-23-spiroketals. Novel cholestanic frameworks with pyranone and cyclopentenone E rings on the side chain.
Steroids 77(5) , 534-41, (2012) The regioselective opening of the F ring of 22-oxo-23-spiroketals using a saturated solution of HCl in acetic anhydride yielded novel cholestanic frameworks with pyranone or cyclopentenone E rings. The structures of the new derivatives of sarsasapogenin, dios... |
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Identification of stable cytotoxic factors in the gas phase extract of cigarette smoke and pharmacological characterization of their cytotoxicity.
Toxicology 314(1) , 1-10, (2013) Smoking is a major risk factor for atherosclerotic vascular diseases, but the mechanism for its genesis is unknown. We have recently shown that the gas phase of cigarette smoke (nicotine- and tar-free cigarette smoke extract; CSE) likely to reach the systemic... |
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Enantioselective synthesis of 5,7-bicyclic ring systems from axially chiral allenes using a Rh(I)-catalyzed cyclocarbonylation reaction.
J. Org. Chem. 78(8) , 3737-54, (2013) A transfer of chirality in an intramolecular Rh(I)-catalyzed allenic Pauson-Khand reaction (APKR) to access tetrahydroazulenones, tetrahydrocyclopenta[c]azepinones and dihydrocyclopenta[c]oxepinones enantioselectively (22-99% ee) is described. The substitutio... |
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TGA transcription factors and jasmonate-independent COI1 signalling regulate specific plant responses to reactive oxylipins.
J. Exp. Bot. 64(4) , 963-75, (2013) Jasmonates and phytoprostanes are oxylipins that regulate stress responses and diverse physiological and developmental processes. 12-Oxo-phytodienoic acid (OPDA) and phytoprostanes are structurally related electrophilic cyclopentenones, which activate similar... |
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O-Monoacyltartaric acid catalyzed enantioselective conjugate addition of a boronic acid to dienones: application to the synthesis of optically active cyclopentenones.
Org. Lett. 16(19) , 5172-5, (2014) Enantioselective conjugate addition of styrylboronic acid to dienones was effectively catalyzed by an O-monoacyltartaric acid to afford monostyrylated products with good enantioselectivity. The RCM of the monostyrylated products using the Hoveyda-Grubbs II ca... |
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Diastereoselective [4 + 1] cycloaddition of alkenyl propargyl acetates with CO catalyzed by [RhCl(CO)2]2.
J. Org. Chem. 77(14) , 6215-22, (2012) A class of alkenyl propargyl acetates, RCH(OAc)C≡CC(CH(3))═CH(2) (5), are found to undergo [4 + 1] cycloaddition with CO (1 atm) in the presence of [RhCl(CO)(2)](2) in refluxing 1,2-dichloroethane to give cyclopentenones (6) in good yields. It has been demons... |
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Diastereoselective synthesis of vicinal tertiary diols.
Org. Lett. 15(8) , 1930-3, (2013) A strategy for the synthesis of differentiated vicinal tertiary diols is described. The key step is a high-yielding, diastereoselective LaCl3·2LiCl-mediated addition of a Grignard or organolithium reagent to ketone 2a. The reaction is believed to proceed via ... |