培氟沙星
培氟沙星结构式
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常用名 | 培氟沙星 | 英文名 | Pefloxacin mesylate dihydrate |
|---|---|---|---|---|
| CAS号 | 149676-40-4 | 分子量 | 465.49400 | |
| 密度 | N/A | 沸点 | 529.1ºC at 760mmHg | |
| 分子式 | C18H28FN3O8S | 熔点 | 271ºC | |
| MSDS | 中文版 美版 | 闪点 | 273.8ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Pefloxacin-induced achilles tendon toxicity in rodents: biochemical changes in proteoglycan synthesis and oxidative damage to collagen.
Antimicrob. Agents Chemother. 44 , 867-872, (2000) Despite a relatively low incidence of serious side effects, fluoroquinolones and the fluoroquinolone pefloxacin have been reported to occasionally promote tendinopathy that might result in the complication of spontaneous rupture of tendons. In the present stu... |
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Cytotoxicity and uptake of pefloxacin, ciprofloxacin, and ofloxacin in primary cultures of rat hepatocytes.
J. Antimicrob. Chemother. 24 , 355-363, (1989) The cytotoxicity and the uptake of three 4-quinolones--pefloxacin, ciprofloxacin, and ofloxacin--were investigated in primary cultures of rat hepatocytes. As assessed by intracellular enzyme release in culture media, pefloxacin at concentration 400 mg/l and c... |
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