Pefloxacin mesylate dihydrate
Pefloxacin mesylate dihydrate structure
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Common Name | Pefloxacin mesylate dihydrate | ||
|---|---|---|---|---|
| CAS Number | 149676-40-4 | Molecular Weight | 465.49400 | |
| Density | N/A | Boiling Point | 529.1ºC at 760mmHg | |
| Molecular Formula | C18H28FN3O8S | Melting Point | 271ºC | |
| MSDS | Chinese USA | Flash Point | 273.8ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Pefloxacin-induced achilles tendon toxicity in rodents: biochemical changes in proteoglycan synthesis and oxidative damage to collagen.
Antimicrob. Agents Chemother. 44 , 867-872, (2000) Despite a relatively low incidence of serious side effects, fluoroquinolones and the fluoroquinolone pefloxacin have been reported to occasionally promote tendinopathy that might result in the complication of spontaneous rupture of tendons. In the present stu... |
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Cytotoxicity and uptake of pefloxacin, ciprofloxacin, and ofloxacin in primary cultures of rat hepatocytes.
J. Antimicrob. Chemother. 24 , 355-363, (1989) The cytotoxicity and the uptake of three 4-quinolones--pefloxacin, ciprofloxacin, and ofloxacin--were investigated in primary cultures of rat hepatocytes. As assessed by intracellular enzyme release in culture media, pefloxacin at concentration 400 mg/l and c... |
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