GW-803430
GW-803430结构式
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常用名 | GW-803430 | 英文名 | GW 803430 |
|---|---|---|---|---|
| CAS号 | 515141-51-2 | 分子量 | 481.99400 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C25H24ClN3O3S | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
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Preclinical evaluation of melanin-concentrating hormone receptor 1 antagonism for the treatment of obesity and depression.
J. Pharmacol. Exp. Ther. 329(2) , 429-38, (2009) The mammalian neuropeptide, melanin-concentrating hormone, interacts with two G protein-coupled receptors, melanin-concentrating hormone receptor (MCHR) 1 and MCHR2; however, only MCHR1 is expressed in rats and mice. In the present study, we evaluated MCHR1 a... |
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Suppression of alcohol self-administration and reinstatement of alcohol seeking by melanin-concentrating hormone receptor 1 (MCH1-R) antagonism in Wistar rats.
Psychopharmacology 211(4) , 367-75, (2010) Melanin-concentrating hormone (MCH) is involved in regulation of appetitive behaviors as well as emotional reactivity and reward, behavioral domains relevant to alcohol addiction.We evaluated the effects of the non-peptide MCH1 receptor antagonist, GW803430 [... |
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