GW 803430
GW 803430 structure
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Common Name | GW 803430 | ||
|---|---|---|---|---|
| CAS Number | 515141-51-2 | Molecular Weight | 481.99400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H24ClN3O3S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Preclinical evaluation of melanin-concentrating hormone receptor 1 antagonism for the treatment of obesity and depression.
J. Pharmacol. Exp. Ther. 329(2) , 429-38, (2009) The mammalian neuropeptide, melanin-concentrating hormone, interacts with two G protein-coupled receptors, melanin-concentrating hormone receptor (MCHR) 1 and MCHR2; however, only MCHR1 is expressed in rats and mice. In the present study, we evaluated MCHR1 a... |
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Suppression of alcohol self-administration and reinstatement of alcohol seeking by melanin-concentrating hormone receptor 1 (MCH1-R) antagonism in Wistar rats.
Psychopharmacology 211(4) , 367-75, (2010) Melanin-concentrating hormone (MCH) is involved in regulation of appetitive behaviors as well as emotional reactivity and reward, behavioral domains relevant to alcohol addiction.We evaluated the effects of the non-peptide MCH1 receptor antagonist, GW803430 [... |
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