芹菜素; 芹黄素; 5,7,4'-三羟基黄酮
芹菜素; 芹黄素; 5,7,4'-三羟基黄酮结构式
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常用名 | 芹菜素; 芹黄素; 5,7,4'-三羟基黄酮 | 英文名 | Apigenin |
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| CAS号 | 520-36-5 | 分子量 | 270.237 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | 555.5±50.0 °C at 760 mmHg | |
| 分子式 | C15H10O5 | 熔点 | >300 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 217.1±23.6 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Rapid evaluation and comparison of natural products and antioxidant activity in calendula, feverfew, and German chamomile extracts.
J. Chromatogr. A. 1385 , 103-10, (2015) The present study describes a simple high performance thin layer chromatographic (HPTLC) method for the simultaneous quantification of apigenin, chamazulene, bisabolol and the use of DPPH free radical as a post-chromatographic derivatization agent to compare ... |
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Effects of flavonoids on senescence-associated secretory phenotype formation from bleomycin-induced senescence in BJ fibroblasts.
Biochem. Pharmacol. 96 , 337-48, (2015) During senescence, cells express molecules called senescence-associated secretory phenotype (SASP), including growth factors, proinflammatory cytokines, chemokines, and proteases. The SASP induces a chronic low-grade inflammation adjacent to cells and tissues... |
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Apigenin induces caspase-dependent apoptosis by inhibiting signal transducer and activator of transcription 3 signaling in HER2-overexpressing SKBR3 breast cancer cells.
Mol. Med. Report. 12 , 2977-84, (2015) Phytoestrogens have been demonstrated to inhibit tumor induction; however, their molecular mechanisms of action have remained elusive. The present study aimed to investigate the effects of a phytoestrogen, apigenin, on proliferation and apoptosis of the human... |
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Membrane transport of nobilin conjugation products and use of the extract of Chamomillae romanae flos influence absorption of nobilin in the Caco-2 model.
Eur. J. Pharm. Sci. 70 , 92-106, (2015) The purpose of this work was to investigate the role of bioconjugation and carrier mediated efflux of conjugation products in the absorption mechanism of the sesquiterpene lactone nobilin in the Caco-2 model in vitro and to elucidate the impact of the extract... |
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Differential metabolomic analysis of the potential antiproliferative mechanism of olive leaf extract on the JIMT-1 breast cancer cell line.
J. Pharm. Biomed. Anal. 105 , 156-62, (2015) A new differential metabolomic approach has been developed to identify the phenolic cellular metabolites derived from breast cancer cells treated with a supercritical fluid extracted (SFE) olive leaf extract. The SFE extract was previously shown to have signi... |
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Effect of extrusion on phytochemical profiles in milled fractions of black rice.
Food Chem. 178 , 186-94, (2015) The phytochemical profile and antioxidant activities of unprocessed and extruded milled fractions of black rice were investigated. Extrusion increased the free phenolics, anthocyanins and oxygen radical absorbance capacity (ORAC) and decreased the bound forms... |
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DNA-Linked Enzyme-Coupled Assay for Probing Glucosyltransferase Specificity.
ACS Synth. Biol. 4 , 833-41, (2015) Traditional enzyme characterization methods are low-throughput and therefore limit engineering efforts in synthetic biology and biotechnology. Here, we propose a DNA-linked enzyme-coupled assay (DLEnCA) to monitor enzyme reactions in a high-throughput manner.... |
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Activity-guided isolation, identification and quantification of biologically active isomeric compounds from folk medicinal plant Desmodium adscendens using high performance liquid chromatography with diode array detector, mass spectrometry and multidimentional nuclear magnetic resonance spectroscopy.
J. Pharm. Biomed. Anal. 102 , 54-63, (2014) The antioxidant activity of the crude extract (60% ethanol) from the leaves of Desmodium adscendens (Sw.) DC. (Fabaceae) was observed in DPPH, xanthine/xanthine oxidase, lipid peroxydation and neutrophils burst tests. Further activity-guided fractionation on ... |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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New Polyphenols Identified in Artemisiae abrotani herba Extract.
Molecules 20 , 11063-75, (2015) Artemisia abrotanum L. ("southernwood") belongs to the Artemisia genus and it is used in traditional medicine for the treatment of a variety of illnesses. Scarce data is available on the chemical composition of this medicinal plant, most research being focuse... |