法呢醇
法呢醇结构式
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常用名 | 法呢醇 | 英文名 | farnesol |
|---|---|---|---|---|
| CAS号 | 4602-84-0 | 分子量 | 222.366 | |
| 密度 | 0.9±0.1 g/cm3 | 沸点 | 283.4±0.0 °C at 760 mmHg | |
| 分子式 | C15H26O | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 96.1±0.0 °C | |
| 符号 |
GHS07, GHS09 |
信号词 | Warning |
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Developmentally regulated sesquiterpene production confers resistance to Colletotrichum gloeosporioides in ripe pepper fruits.
PLoS ONE 9(10) , e109453, (2014) Sesquiterpenoid capsidiol, exhibiting antifungal activity against pathogenic fungus, is accumulated in infected ripe pepper fruits. In this study, we found a negative relation between the capsidiol level and lesion size in fruits infected with Colletotrichum ... |
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Farnesol induces apoptosis-like cell death in the pathogenic fungus Aspergillus flavus.
Mycologia 106(5) , 881-8, (2014) Farnesol (FOH) is known to induce apoptosis in some fungi and mammalian cells. We treated Aspergillus flavus, one of the leading causes of human invasive aspergillosis and a key producer of the most potent naturally occurring hepatocarcinogenic compounds, wit... |
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Pluronics-Formulated Farnesol Promotes Efficient Killing and Demonstrates Novel Interactions with Streptococcus mutans Biofilms.
PLoS ONE 10 , e0133886, (2015) Streptococcus mutans is the primary causative agent of dental caries, one of the most prevalent diseases in the United States. Previously published studies have shown that Pluronic-based tooth-binding micelles carrying hydrophobic antimicrobials are extremely... |
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pH-activated nanoparticles for controlled topical delivery of farnesol to disrupt oral biofilm virulence.
ACS Nano 9(3) , 2390-404, (2015) Development of effective therapies to control oral biofilms is challenging, as topically introduced agents must avoid rapid clearance from biofilm-tooth interfaces while targeting biofilm microenvironments. Additionally, exopolysaccharides-matrix and acidific... |
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Quantification of nerolidol in mouse plasma using gas chromatography-mass spectrometry.
J. Pharm. Biomed. Anal. 111 , 100-3, (2015) Nerolidol is a naturally occurring sesquiterpene found in the essential oils of many types of flowers and plants. It is frequently used in cosmetics, as a food flavoring agent, and in cleaning products. In addition, nerolidol is used as a skin penetration enh... |
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Anti-cancer potential of MAPK pathway inhibition in paragangliomas-effect of different statins on mouse pheochromocytoma cells.
PLoS ONE 9(5) , e97712, (2014) To date, malignant pheochromocytomas and paragangliomas (PHEOs/PGLs) cannot be effectively cured and thus novel treatment strategies are urgently needed. Lovastatin has been shown to effectively induce apoptosis in mouse PHEO cells (MPC) and the more aggressi... |
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C-geranylated chalcones from the stems of Angelica keiskei with superoxide-scavenging activity.
J. Nat. Prod. 71 , 1308-10, (2008) An ethyl acetate-soluble fraction of a methanol extract from the stems of Angelica keiskei was subjected to chromatographic separation to give three new chalcones, designated as xanthokeismins A-C (1-3), in addition to a known chalcone, xanthoangelol B (4). T... |
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Effect of Trans, Trans-Farnesol on Pseudogymnoascus destructans and Several Closely Related Species.
Mycopathologia 180 , 325-32, (2015) Bat white-nose syndrome, caused by the psychrophilic fungus Pseudogymnoascus destructans, has dramatically reduced the populations of many hibernating North American bat species. The search for effective biological control agents targeting P. destructans is o... |
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The Bax inhibitor MrBI-1 regulates heat tolerance, apoptotic-like cell death, and virulence in Metarhizium robertsii.
Sci. Rep. 5 , 10625, (2015) Bax inhibitor 1 (BI-1) is a highly conserved protein originally identified as a suppressor of the proapoptotic protein Bax to inhibit cell death in animals and plants. The orthologs of BI-1 are widely distributed in filamentous fungi but their functions remai... |
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Quercetin sensitizes fluconazole-resistant candida albicans to induce apoptotic cell death by modulating quorum sensing.
Antimicrob. Agents Chemother. 59 , 2153-68, (2015) Quorum sensing (QS) regulates group behaviors of Candida albicans such as biofilm, hyphal growth, and virulence factors. The sesquiterpene alcohol farnesol, a QS molecule produced by C. albicans, is known to regulate the expression of virulence weapons of thi... |