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(R)-1-Boc-3-羟基吡咯烷

(R)-1-Boc-3-羟基吡咯烷结构式
(R)-1-Boc-3-羟基吡咯烷结构式
品牌特惠专场
常用名 (R)-1-Boc-3-羟基吡咯烷 英文名 (R)-(-)-N-Boc-3-pyrrolidinol
CAS号 109431-87-0 分子量 187.24
密度 1.1±0.1 g/cm3 沸点 273.3±33.0 °C at 760 mmHg
分子式 C9H17NO3 熔点 62-65 °C(lit.)
MSDS 中文版 美版 闪点 119.1±25.4 °C
符号 GHS07 GHS09
GHS07, GHS09
信号词 Warning

Design, synthesis and biological activity of amidinobicyclic compounds (derivatives of DX-9065a) as factor Xa inhibitors: SAR study of S1 and aryl binding sites.

Bioorg. Med. Chem. 12 , 2099-2114, (2004)

Since factor Xa (fXa) plays a pivotal role in the blood coagulation cascade, inhibition of fXa is thought to be an effective treatment for a variety of thrombotic events. (2S)-2-[4-[[(3S)-1-Acetimidoyl-3-pyrrolidinyl]oxy]phenyl]-3-(7-amidino-2-naphthyl)propan...

Synthesis and structure-activity relationship of novel pyridyl ethers for the nicotinic acetylcholine receptor.

Bioorg. Med. Chem. Lett. 10 , 1063, (2000)

The preparation of novel pyridyl ethers as ligands for the nicotinic acetylcholine receptor (nAChR) is described. Variations of the ring size of the azacycle and substitution on the pyridine had dramatic effects on receptor binding affinity with IC50s at the ...