(R)-(-)-N-Boc-3-pyrrolidinol

(R)-(-)-N-Boc-3-pyrrolidinol Structure
(R)-(-)-N-Boc-3-pyrrolidinol structure
Common Name (R)-(-)-N-Boc-3-pyrrolidinol
CAS Number 109431-87-0 Molecular Weight 187.24
Density 1.1±0.1 g/cm3 Boiling Point 273.3±33.0 °C at 760 mmHg
Molecular Formula C9H17NO3 Melting Point 62-65 °C(lit.)
MSDS Chinese USA Flash Point 119.1±25.4 °C
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

Design, synthesis and biological activity of amidinobicyclic compounds (derivatives of DX-9065a) as factor Xa inhibitors: SAR study of S1 and aryl binding sites.

Bioorg. Med. Chem. 12 , 2099-2114, (2004)

Since factor Xa (fXa) plays a pivotal role in the blood coagulation cascade, inhibition of fXa is thought to be an effective treatment for a variety of thrombotic events. (2S)-2-[4-[[(3S)-1-Acetimidoyl-3-pyrrolidinyl]oxy]phenyl]-3-(7-amidino-2-naphthyl)propan...

Synthesis and structure-activity relationship of novel pyridyl ethers for the nicotinic acetylcholine receptor.

Bioorg. Med. Chem. Lett. 10 , 1063, (2000)

The preparation of novel pyridyl ethers as ligands for the nicotinic acetylcholine receptor (nAChR) is described. Variations of the ring size of the azacycle and substitution on the pyridine had dramatic effects on receptor binding affinity with IC50s at the ...