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4-氯-2,8-双(三氟甲基)喹啉

4-氯-2,8-双(三氟甲基)喹啉结构式
4-氯-2,8-双(三氟甲基)喹啉结构式
品牌特惠专场
常用名 4-氯-2,8-双(三氟甲基)喹啉 英文名 4-chloro-2,8-di(trifluoromethyl)quinoline
CAS号 83012-13-9 分子量 299.600
密度 1.5±0.1 g/cm3 沸点 251.8±35.0 °C at 760 mmHg
分子式 C11H4ClF6N 熔点 46-48 °C(lit.)
MSDS 中文版 美版 闪点 106.1±25.9 °C
符号 GHS07
GHS07
信号词 Warning

New quinoline derivatives: synthesis and investigation of antibacterial and antituberculosis properties.

Eur. J. Med. Chem. 45 , 3374, (2010)

Four new series of quinoline derivatives were synthesized starting from 2-trifluoromethyl aniline through multi-step reactions. In the reaction sequence, substituted aniline was cyclized to 4-hydroxy quinoline 1, which was then transformed to 4-chloro-2,8-bis...