4-chloro-2,8-di(trifluoromethyl)quinoline

4-chloro-2,8-di(trifluoromethyl)quinoline Structure
4-chloro-2,8-di(trifluoromethyl)quinoline structure
Common Name 4-chloro-2,8-di(trifluoromethyl)quinoline
CAS Number 83012-13-9 Molecular Weight 299.600
Density 1.5±0.1 g/cm3 Boiling Point 251.8±35.0 °C at 760 mmHg
Molecular Formula C11H4ClF6N Melting Point 46-48 °C(lit.)
MSDS Chinese USA Flash Point 106.1±25.9 °C
Symbol GHS07
GHS07
Signal Word Warning

New quinoline derivatives: synthesis and investigation of antibacterial and antituberculosis properties.

Eur. J. Med. Chem. 45 , 3374, (2010)

Four new series of quinoline derivatives were synthesized starting from 2-trifluoromethyl aniline through multi-step reactions. In the reaction sequence, substituted aniline was cyclized to 4-hydroxy quinoline 1, which was then transformed to 4-chloro-2,8-bis...