细胞松弛素A
细胞松弛素A结构式
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常用名 | 细胞松弛素A | 英文名 | Cytochalasin A |
|---|---|---|---|---|
| CAS号 | 14110-64-6 | 分子量 | 477.592 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 725.1±60.0 °C at 760 mmHg | |
| 分子式 | C29H35NO5 | 熔点 | 147 to 148'ºC | |
| MSDS | 美版 | 闪点 | 392.3±32.9 °C | |
| 符号 |
GHS06, GHS08 |
信号词 | Danger |
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Apical growth and mitosis are independent processes in Aspergillus nidulans.
Protoplasma 222(3-4) , 211-5, (2003) It is well established that cytoplasmic microtubules are depolymerized during nuclear division and reassembled as mitotic microtubules. Mounting evidence showing that cytoplasmic microtubules were also involved in apical growth of fungal hyphae posed the ques... |
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Roles of the actin cytoskeleton and an actin-binding protein in wheat resistance against Puccinia striiformis f. sp. tritici.
Protoplasma 249(1) , 99-106, (2012) Elucidating resistance mechanisms of plant cells against pathogens is essential to develop novel strategies of disease control. The actin cytoskeleton was found intimately involved in plant defense. In order to reveal how actin would be involved in the intera... |
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Preferential phosphorylation of focal adhesion kinase tyrosine 861 is critical for mediating an anti-apoptotic response to hyperosmotic stress.
J. Biol. Chem. 282(14) , 10370-9, (2007) The results presented here demonstrate that focal adhesion kinase (FAK) Tyr-861 is the predominant tyrosine phosphorylation site stimulated by hyperosmotic stress in a variety of cell types, including epithelial cell lines (ileum-derived IEC-18, colon-derived... |
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Localization of RHO-4 indicates differential regulation of conidial versus vegetative septation in the filamentous fungus Neurospora crassa.
Eukaryotic Cell 6(7) , 1097-107, (2007) Rho-4 mutants of the filamentous fungus Neurospora crassa lack septa and asexual spores (conidia) and grow slowly. In this report, localization of green fluorescent protein-tagged RHO-4 is used to elucidate the differences in factors controlling RHO-4 localiz... |
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Role of actin cytoskeletal dynamics in activation of the cyclic AMP pathway and HWP1 gene expression in Candida albicans.
Eukaryotic Cell 6(10) , 1824-40, (2007) Changes in gene expression during reversible bud-hypha transitions of the opportunistic fungal pathogen Candida albicans permit adaptation to environmental conditions that are critical for proliferation in host tissues. Our previous work has shown that the hy... |
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Giardia lamblia behavior under cytochalasins treatment.
Parasitol. Res. 98(3) , 250-6, (2006) Giardia lamblia, a flagellated protist, is the parasite most commonly found in the intestinal tract of humans and other mammals causing a disease known as giardiasis. This parasite presents several cytoskeletal structures whose major components are microtubul... |
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RGD-containing peptides and cyclic AMP have antagonistic roles in the morphology of Mucor rouxii.
Protoplasma 222(1-2) , 23-30, (2003) The tripeptide Arg-Gly-Asp (RGD) (1 mM) as well as the polymer ProNectin F (20 nM) added to culture medium of the fungus Mucor rouxii (defined medium) produced a delay in the switch from isodiametric growth to tip growth; at the time of germination the mother... |
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Cyclase-associated protein is essential for the functioning of the endo-lysosomal system and provides a link to the actin cytoskeleton.
Traffic 6(10) , 930-46, (2005) Data from mutant analysis in yeast and Dictyostelium indicate a role for the cyclase-associated protein (CAP) in endocytosis and vesicle transport. We have used genetic and biochemical approaches to identify novel interacting partners of Dictyostelium CAP to ... |
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Effects of medium calcium, and agents affecting cytoskeletal function, on cellular volume and morphology in liver tissue in vitro.
J. Cell. Biochem. 113(6) , 1915-25, (2012) The possible role of an exocytotic, vesicular mechanism in cellular volume regulation under iso-osmotic conditions has been studied in slices of rat liver. The effects of incubation conditions and agents affecting the actin cytoskeleton were examined for chan... |
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PKC-dependent stimulation of EAAT3 glutamate transporter does not require the integrity of actin cytoskeleton.
Neurochem. Int. 48(5) , 341-9, (2006) The activity and the membrane expression of EAAT3 glutamate transporter are stimulated upon PKC activation by phorbol esters in C6 rat glioma cells. To investigate the role of cytoskeleton in these effects, we have employed actin-perturbing toxins and found t... |