5′-脱氧-5′-(甲硫基)腺苷
5′-脱氧-5′-(甲硫基)腺苷结构式
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常用名 | 5′-脱氧-5′-(甲硫基)腺苷 | 英文名 | Adenylthiomethylpentose |
|---|---|---|---|---|
| CAS号 | 2457-80-9 | 分子量 | 297.333 | |
| 密度 | 1.9±0.1 g/cm3 | 沸点 | 642.7±65.0 °C at 760 mmHg | |
| 分子式 | C11H15N5O3S | 熔点 | 210-213ºC (dec.) | |
| MSDS | 中文版 美版 | 闪点 | 342.5±34.3 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Long-acting progestin-only contraceptives impair endometrial vasculature by inhibiting uterine vascular smooth muscle cell survival.
Proc. Natl. Acad. Sci. U. S. A. 112(16) , 5153-8, (2015) Molecular mechanisms responsible for abnormal endometrial vasculature in women receiving long-acting progestin-only contraceptives (LAPCs) are unknown. We hypothesize that LAPCs impair vascular smooth muscle cell (VSMC) and pericyte proliferation and migratio... |
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Differential expression of glial-derived neurotrophic factor in rat laryngeal muscles during reinnervation.
Laryngoscope 124(12) , 2750-6, (2014) Nonspecific, synkinetic reinnervation is one of the causes of poor functional recovery after a peripheral nerve lesion. Knowledge of the differential expression of neurotrophic factors that subserve axon guidance, as well as neuromuscular junction formation a... |
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Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma.
Nat. Commun. 5 , 5712, (2014) Increased expression of the Microphthalmia-associated transcription factor (MITF) contributes to melanoma progression and resistance to BRAF pathway inhibition. Here we show that the lack of MITF is associated with more severe resistance to a range of inhibit... |
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Exometabolom analysis of breast cancer cell lines: Metabolic signature.
Sci. Rep. 5 , 13374, (2015) Cancer cells show characteristic effects on cellular turnover and DNA/RNA modifications leading to elevated levels of excreted modified nucleosides. We investigated the molecular signature of different subtypes of breast cancer cell lines and the breast epith... |
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Metallothionein from Pseudosciaena crocea: expression and response to cadmium-induced injury in the testes.
Ecotoxicology 24(4) , 779-94, (2015) Metallothioneins (MTs) are a family of stress proteins that are involved in the process of detoxification and anti-oxidation. Previous studies have focused mostly on the expression and functions of MTs in the non-reproductive tissues of aquatic vertebrates. H... |
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An unexpected role for mixotrophs in the response of peatland carbon cycling to climate warming.
Sci. Rep. 5 , 16931, (2015) Mixotrophic protists are increasingly recognized for their significant contribution to carbon (C) cycling. As phototrophs they contribute to photosynthetic C fixation, whilst as predators of decomposers, they indirectly influence organic matter decomposition.... |
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A bioinformatic and mechanistic study elicits the antifibrotic effect of ursolic acid through the attenuation of oxidative stress with the involvement of ERK, PI3K/Akt, and p38 MAPK signaling pathways in human hepatic stellate cells and rat liver.
Drug Des. Devel. Ther. 9 , 3989-4104, (2015) NADPH oxidases (NOXs) are a predominant mediator of redox homeostasis in hepatic stellate cells (HSCs), and oxidative stress plays an important role in the pathogenesis of liver fibrosis. Ursolic acid (UA) is a pentacyclic triterpenoid with various pharmacolo... |
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Survival characteristics of composite restorations in primary teeth.
Clin. Oral Investig. 19 , 1653-62, (2015) This retrospective study analyzed restoration survival of composite fillings in children with at high caries risk in relation to age, sex, operator, tooth type, filling extension, and material used.Among 667 children treated in 2004-2012 in a university setti... |
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Pulp Revascularization of Immature Dog Teeth with Apical Periodontitis Using Triantibiotic Paste and Platelet-rich Plasma: A Radiographic Study.
J. Endod. 41 , 1299-304, (2015) This study evaluates radiographically the efficacy of 4 revascularization protocols in necrotic-infected immature dog teeth with apical periodontitis (AP).Forty double-rooted immature premolar teeth from 4 female beagle dogs aged 5 months were used. Four teet... |
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Antibacterial and Odontogenesis Efficacy of Mineral Trioxide Aggregate Combined with CO2 Laser Treatment.
J. Endod. 41 , 1073-80, (2015) Mineral trioxide aggregate (MTA) has been successfully used in clinical applications in endodontics. Studies show that the antibacterial effects of CO2 laser irradiation are highly efficient when bacteria are embedded in biofilm because of a photothermal mech... |