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4-羟基-6-(三氟甲基)嘧啶

4-羟基-6-(三氟甲基)嘧啶结构式
4-羟基-6-(三氟甲基)嘧啶结构式
品牌特惠专场
常用名 4-羟基-6-(三氟甲基)嘧啶 英文名 6-(trifluoromethyl)pyrimidin-4-ol
CAS号 1546-78-7 分子量 164.085
密度 1.5±0.1 g/cm3 沸点 229.0±35.0 °C at 760 mmHg
分子式 C5H3F3N2O 熔点 169-171 °C(lit.)
MSDS 中文版 美版 闪点 92.3±25.9 °C
符号 GHS07
GHS07
信号词 Warning

Synthesis and antitumor activity of novel 10-substituted camptothecin analogues.

Bioorg. Med. Chem. 14(21) , 7175-82, (2006)

In an attempt to improve the antitumor activity and decrease the cytotoxicity of camptothecin, 18 new 10-substituted camptothecin derivatives were prepared. The cytotoxicity in vitro on cancer cell lines and antitumor activity in vivo, and inhibitory properti...