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芳卤芬酯

芳卤芬酯结构式
芳卤芬酯结构式
品牌特惠专场
常用名 芳卤芬酯 英文名 MBX 102
CAS号 24136-23-0 分子量 415.79100
密度 N/A 沸点 N/A
分子式 C19H17ClF3NO4 熔点 N/A
MSDS 中文版 美版 闪点 N/A
符号 GHS06 GHS09
GHS06, GHS09
信号词 Danger

MBX-102/JNJ39659100, a novel peroxisome proliferator-activated receptor-ligand with weak transactivation activity retains antidiabetic properties in the absence of weight gain and edema.

Mol. Endocrinol. 23 , 975-988, (2009)

MBX-102/JNJ39659100 (MBX-102) is in clinical development as an oral glucose-lowering agent for the treatment of type 2 diabetes. MBX-102 is a nonthiazolidinedione (TZD) selective partial agonist of peroxisome proliferator-activated receptor (PPAR)-gamma that ...

MBX-102/JNJ39659100, a novel non-TZD selective partial PPAR-γ agonist lowers triglyceride independently of PPAR-α activation.

PPAR Res. 2009 , 706852, (2009)

MBX-102/JNJ-39659100 (MBX-102) is a selective, partial PPAR-γ agonist that lowers glucose in the absence of some of the side effects, such as weight gain and edema, that are observed with the TZDs. Interestingly MBX-102 also displays pronounced triglyceride l...