![]() 芳卤芬酯结构式
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常用名 | 芳卤芬酯 | 英文名 | MBX 102 |
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CAS号 | 24136-23-0 | 分子量 | 415.79100 | |
密度 | N/A | 沸点 | N/A | |
分子式 | C19H17ClF3NO4 | 熔点 | N/A | |
MSDS | 中文版 美版 | 闪点 | N/A | |
符号 |
![]() ![]() GHS06, GHS09 |
信号词 | Danger |
MBX-102/JNJ39659100, a novel peroxisome proliferator-activated receptor-ligand with weak transactivation activity retains antidiabetic properties in the absence of weight gain and edema.
Mol. Endocrinol. 23 , 975-988, (2009) MBX-102/JNJ39659100 (MBX-102) is in clinical development as an oral glucose-lowering agent for the treatment of type 2 diabetes. MBX-102 is a nonthiazolidinedione (TZD) selective partial agonist of peroxisome proliferator-activated receptor (PPAR)-gamma that ... |
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MBX-102/JNJ39659100, a novel non-TZD selective partial PPAR-γ agonist lowers triglyceride independently of PPAR-α activation.
PPAR Res. 2009 , 706852, (2009) MBX-102/JNJ-39659100 (MBX-102) is a selective, partial PPAR-γ agonist that lowers glucose in the absence of some of the side effects, such as weight gain and edema, that are observed with the TZDs. Interestingly MBX-102 also displays pronounced triglyceride l... |
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