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N-(4-((6,7-DIMETHOXY-4-QUINAZOLINYL)AMIN

N-(4-((6,7-DIMETHOXY-4-QUINAZOLINYL)AMIN结构式
N-(4-((6,7-DIMETHOXY-4-QUINAZOLINYL)AMIN结构式
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常用名 N-(4-((6,7-DIMETHOXY-4-QUINAZOLINYL)AMIN 英文名 N-(4-((6,7-DIMETHOXY-4-QUINAZOLINYL)AMIN
CAS号 179247-42-8 分子量 436.89100
密度 N/A 沸点 N/A
分子式 C23H21ClN4O3 熔点 N/A
MSDS 中文版 美版 闪点 N/A
符号 GHS07
GHS07
信号词 Warning

SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors.

Bioorg. Med. Chem. Lett. 16 , 1320-1323, (2006)

A novel series of 5-aminopyrimidinyl quinazolines has been developed from anilino-quinazoline 1, which was identified in a high throughput screen for Aurora A. Introduction of the pyrimidine ring and optimisation of the substituents both on this ring and at t...