N-(4-((6,7-DIMETHOXY-4-QUINAZOLINYL)AMIN

N-(4-((6,7-DIMETHOXY-4-QUINAZOLINYL)AMIN Structure
N-(4-((6,7-DIMETHOXY-4-QUINAZOLINYL)AMIN structure
Common Name N-(4-((6,7-DIMETHOXY-4-QUINAZOLINYL)AMIN
CAS Number 179247-42-8 Molecular Weight 436.89100
Density N/A Boiling Point N/A
Molecular Formula C23H21ClN4O3 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors.

Bioorg. Med. Chem. Lett. 16 , 1320-1323, (2006)

A novel series of 5-aminopyrimidinyl quinazolines has been developed from anilino-quinazoline 1, which was identified in a high throughput screen for Aurora A. Introduction of the pyrimidine ring and optimisation of the substituents both on this ring and at t...