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DESMOSINE STANDARD

DESMOSINE STANDARD结构式
DESMOSINE STANDARD结构式
委托求购
常用名 DESMOSINE STANDARD 英文名 DESMOSINE STANDARD
CAS号 10019-68-8 分子量 562.05600
密度 N/A 沸点 N/A
分子式 C24H40ClN5O8 熔点 N/A
MSDS 中文版 美版 闪点 N/A

Urinary desmosine excretion is inversely correlated with the extent of emphysema in patients with chronic obstructive pulmonary disease.

Int. J. Biochem. Cell Biol. 34 , 594-604, (2002)

An enhanced proteolysis of lung interstitium is key event in the pathogenesis of emphysema, a major constituent of chronic obstructive pulmonary disease. To assess whether urinary desmosine and/or hydroxyproline may be used as a marker of lung destruction we ...

Elastin degradation and calcification in an abdominal aorta injury model: role of matrix metalloproteinases.

Circulation 110 , 3480-3487, (2004)

Elastin calcification is a widespread feature of vascular pathology, and circumstantial evidence exists for a correlation between elastin degradation and calcification. We hypothesized that matrix metalloproteinase (MMP)-mediated vascular remodeling plays a s...

Aluminum chloride pretreatment of elastin inhibits elastolysis by matrix metalloproteinases and leads to inhibition of elastin-oriented calcification.

Am. J. Pathol. 159 , 1981-1986, (2001)

Calcification of elastin occurs in many pathological cardiovascular diseases including atherosclerosis. We have previously shown that purified elastin when subdermally implanted in rats undergoes severe calcification and aluminum chloride (AlCl(3)) pretreatme...