DESMOSINE STANDARD structure
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Common Name | DESMOSINE STANDARD | ||
|---|---|---|---|---|
| CAS Number | 10019-68-8 | Molecular Weight | 562.05600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H40ClN5O8 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Name | 2-amino-6-[4-(4-amino-4-carboxybutyl)-3,5-bis(3-amino-3-carboxypropyl)pyridin-1-ium-1-yl]hexanoic acid,chloride |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C24H40ClN5O8 |
|---|---|
| Molecular Weight | 562.05600 |
| Exact Mass | 561.25700 |
| PSA | 257.16000 |
| InChIKey | FUPMLZCXPJSGPV-UHFFFAOYSA-N |
| SMILES | NC(CCCC[n+]1cc(CCC(N)C(=O)O)c(CCCC(N)C(=O)O)c(CCC(N)C(=O)O)c1)C(=O)O.[Cl-] |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
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Urinary desmosine excretion is inversely correlated with the extent of emphysema in patients with chronic obstructive pulmonary disease.
Int. J. Biochem. Cell Biol. 34 , 594-604, (2002) An enhanced proteolysis of lung interstitium is key event in the pathogenesis of emphysema, a major constituent of chronic obstructive pulmonary disease. To assess whether urinary desmosine and/or hyd... |
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Elastin degradation and calcification in an abdominal aorta injury model: role of matrix metalloproteinases.
Circulation 110 , 3480-3487, (2004) Elastin calcification is a widespread feature of vascular pathology, and circumstantial evidence exists for a correlation between elastin degradation and calcification. We hypothesized that matrix met... |
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Aluminum chloride pretreatment of elastin inhibits elastolysis by matrix metalloproteinases and leads to inhibition of elastin-oriented calcification.
Am. J. Pathol. 159 , 1981-1986, (2001) Calcification of elastin occurs in many pathological cardiovascular diseases including atherosclerosis. We have previously shown that purified elastin when subdermally implanted in rats undergoes seve... |
| Desmosine chloride |