DESMOSINE STANDARD
DESMOSINE STANDARD structure
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Common Name | DESMOSINE STANDARD | ||
|---|---|---|---|---|
| CAS Number | 10019-68-8 | Molecular Weight | 562.05600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H40ClN5O8 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Urinary desmosine excretion is inversely correlated with the extent of emphysema in patients with chronic obstructive pulmonary disease.
Int. J. Biochem. Cell Biol. 34 , 594-604, (2002) An enhanced proteolysis of lung interstitium is key event in the pathogenesis of emphysema, a major constituent of chronic obstructive pulmonary disease. To assess whether urinary desmosine and/or hydroxyproline may be used as a marker of lung destruction we ... |
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Elastin degradation and calcification in an abdominal aorta injury model: role of matrix metalloproteinases.
Circulation 110 , 3480-3487, (2004) Elastin calcification is a widespread feature of vascular pathology, and circumstantial evidence exists for a correlation between elastin degradation and calcification. We hypothesized that matrix metalloproteinase (MMP)-mediated vascular remodeling plays a s... |
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Aluminum chloride pretreatment of elastin inhibits elastolysis by matrix metalloproteinases and leads to inhibition of elastin-oriented calcification.
Am. J. Pathol. 159 , 1981-1986, (2001) Calcification of elastin occurs in many pathological cardiovascular diseases including atherosclerosis. We have previously shown that purified elastin when subdermally implanted in rats undergoes severe calcification and aluminum chloride (AlCl(3)) pretreatme... |