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硫酸粘杆菌素

硫酸粘杆菌素结构式
硫酸粘杆菌素结构式
品牌特惠专场
常用名 硫酸粘杆菌素 英文名 Colistin sulfate
CAS号 1264-72-8 分子量 1253.51
密度 1.3±0.1 g/cm3 沸点 1537.3±65.0 °C at 760 mmHg
分子式 C52H100N16O17S 熔点 200-220°C
MSDS 中文版 美版 闪点 883.5±34.3 °C
符号 GHS06
GHS06
信号词 Danger

Inhibitory Effect of Epigallocatechin Gallate on the Virulence of Clostridium difficile PCR Ribotype 027.

J. Food Sci. 80 , M2925-31, (2016)

Clostridium difficile infection (CDI) is the most prevalent cause of health-care-associated infections. CDI-related health-care costs and deaths are both increasing annually on a global scale. C. difficile have been reported in food products in Canada, Europe...

Mucin Binding Reduces Colistin Antimicrobial Activity.

Antimicrob. Agents Chemother. 59 , 5925-31, (2015)

Colistin has found increasing use in treating drug-resistant bacterial lung infections, but potential interactions with pulmonary biomolecules have not been investigated. We postulated that colistin, like aminoglycoside antibiotics, may bind to secretory muci...

Renal disposition of colistin in the isolated perfused rat kidney.

Antimicrob. Agents Chemother. 53 , 2857-64, (2009)

Nephrotoxicity is an important limitation to the clinical use of colistin against Pseudomonas aeruginosa and other gram-negative pathogens. Previous work reported net tubular reabsorption of colistin by the kidney in vivo, but there is no knowledge of its dis...

Activity of cecropin A-melittin hybrid peptides against colistin-resistant clinical strains of Acinetobacter baumannii: molecular basis for the differential mechanisms of action.

Antimicrob. Agents Chemother. 50 , 1251-1256, (2006)

Acinetobacter baumannii has successfully developed resistance against all common antibiotics, including colistin (polymyxin E), the last universally active drug against this pathogen. The possible widespread distribution of colistin-resistant A. baumannii str...

In vitro pharmacodynamic properties of colistin and colistin methanesulfonate against Pseudomonas aeruginosa isolates from patients with cystic fibrosis.

Antimicrob. Agents Chemother. 45 , 781-785, (2001)

The in vitro pharmacodynamic properties of colistin and colistin methanesulfonate were investigated by studying the MICs, time-kill kinetics, and postantibiotic effect (PAE) against mucoid and nonmucoid strains of Pseudomonas aeruginosa isolated from patients...