Colistin sulfate
Colistin sulfate structure
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Common Name | Colistin sulfate | ||
|---|---|---|---|---|
| CAS Number | 1264-72-8 | Molecular Weight | 1253.51 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 1537.3±65.0 °C at 760 mmHg | |
| Molecular Formula | C52H100N16O17S | Melting Point | 200-220°C | |
| MSDS | Chinese USA | Flash Point | 883.5±34.3 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Inhibitory Effect of Epigallocatechin Gallate on the Virulence of Clostridium difficile PCR Ribotype 027.
J. Food Sci. 80 , M2925-31, (2016) Clostridium difficile infection (CDI) is the most prevalent cause of health-care-associated infections. CDI-related health-care costs and deaths are both increasing annually on a global scale. C. difficile have been reported in food products in Canada, Europe... |
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Mucin Binding Reduces Colistin Antimicrobial Activity.
Antimicrob. Agents Chemother. 59 , 5925-31, (2015) Colistin has found increasing use in treating drug-resistant bacterial lung infections, but potential interactions with pulmonary biomolecules have not been investigated. We postulated that colistin, like aminoglycoside antibiotics, may bind to secretory muci... |
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Renal disposition of colistin in the isolated perfused rat kidney.
Antimicrob. Agents Chemother. 53 , 2857-64, (2009) Nephrotoxicity is an important limitation to the clinical use of colistin against Pseudomonas aeruginosa and other gram-negative pathogens. Previous work reported net tubular reabsorption of colistin by the kidney in vivo, but there is no knowledge of its dis... |
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Activity of cecropin A-melittin hybrid peptides against colistin-resistant clinical strains of Acinetobacter baumannii: molecular basis for the differential mechanisms of action.
Antimicrob. Agents Chemother. 50 , 1251-1256, (2006) Acinetobacter baumannii has successfully developed resistance against all common antibiotics, including colistin (polymyxin E), the last universally active drug against this pathogen. The possible widespread distribution of colistin-resistant A. baumannii str... |
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In vitro pharmacodynamic properties of colistin and colistin methanesulfonate against Pseudomonas aeruginosa isolates from patients with cystic fibrosis.
Antimicrob. Agents Chemother. 45 , 781-785, (2001) The in vitro pharmacodynamic properties of colistin and colistin methanesulfonate were investigated by studying the MICs, time-kill kinetics, and postantibiotic effect (PAE) against mucoid and nonmucoid strains of Pseudomonas aeruginosa isolated from patients... |