NNGH
NNGH结构式
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常用名 | NNGH | 英文名 | NNGH |
|---|---|---|---|---|
| CAS号 | 161314-17-6 | 分子量 | 316.373 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | N/A | |
| 分子式 | C13H20N2O5S | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Matrix metalloproteinase-3 causes dopaminergic neuronal death through Nox1-regenerated oxidative stress.
PLoS ONE 9(12) , e115954, (2014) In the present study we investigated the interplay between matrix metalloproteinase 3 (MMP3) and NADPH oxidase 1 (Nox1) in the process of dopamine (DA) neuronal death. We found that MMP3 activation causes the induction of Nox1 via mitochondrial reactive oxyge... |
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Matrix Metalloproteinase-3 Promotes Early Blood–Spinal Cord Barrier Disruption and Hemorrhage and Impairs Long-Term Neurological Recovery after Spinal Cord Injury
Am. J. Pathol. 184(11) , 2985-3000, (2014) After spinal cord injury (SCI), blood–spinal cord barrier (BSCB) disruption by matrix metalloproteinases (MMPs) leads to BSCB permeability and blood cell infiltration, contributing to permanent neurological disability. Herein, we report that MMP-3 plays a cri... |
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Hox10-regulated endodermal cell migration is essential for development of the ascidian intestine.
Dev. Biol. 403 , 43-56, (2015) Hox cluster genes play crucial roles in development of the metazoan antero-posterior axis. Functions of Hox genes in patterning the central nervous system and limb buds are well known. They are also expressed in chordate endodermal tissues, where their roles ... |
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Aberrant production of tenascin-C in globoid cell leukodystrophy alters psychosine-induced microglial functions.
J. Neuropathol. Exp. Neurol. 73(10) , 964-74, (2014) Globoid cell leukodystrophy (GLD), or Krabbe disease, is a rare and often fatal demyelinating disease caused by mutations in the galactocerebrosidase (galc) gene that result in accumulation of galactosylsphingosine (psychosine). We recently reported that the ... |
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Disruption of epithelial barrier by quorum-sensing N-3-(oxododecanoyl)-homoserine lactone is mediated by matrix metalloproteinases.
Am. J. Physiol. Gastrointest. Liver Physiol. 306(11) , G992-G1001, (2014) The intestinal epithelium forms a selective barrier maintained by tight junctions (TJs) and separating the luminal environment from the submucosal tissues. N-acylhomoserine lactone (AHL) quorum-sensing molecules produced by gram-negative bacteria in the gut c... |
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Expression and integrity of dermatopontin in chronic cutaneous wounds: a crucial factor in impaired wound healing.
Cell Tissue Res. 358(3) , 833-41, (2014) Chronic cutaneous wound (CCW) is a major health care burden wherein the healing process is slow or rather static resulting in anatomical and functional restriction of the damaged tissue. Dysregulated expression and degradation of matrix proteins, growth facto... |
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Caspase-9 activation and Apaf-1 cleavage by MMP-3.
Biochem. Biophys. Res. Commun. 453(3) , 563-8, (2014) We have previously demonstrated that matrix metalloprotease-3 (MMP-3) can act inside the cell to trigger apoptosis in response to various cell stresses in dopaminergic neuronal cells. However, the mechanism by which MMP-3 activity leads to caspase-3 activatio... |