B-赤霉醇
B-赤霉醇结构式
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常用名 | B-赤霉醇 | 英文名 | b-Zearalanol |
|---|---|---|---|---|
| CAS号 | 42422-68-4 | 分子量 | 322.396 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 576.0±50.0 °C at 760 mmHg | |
| 分子式 | C18H26O5 | 熔点 | 134-137ºC | |
| MSDS | 中文版 美版 | 闪点 | 207.9±23.6 °C | |
| 符号 |
GHS07, GHS08 |
信号词 | Danger |
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Determination of resorcylic acid lactones in biological samples by GC-MS. Discrimination between illegal use and contamination with fusarium toxins.
Anal. Bioanal. Chem 384(5) , 1221-7, (2006) An EU project, FAIR5-CT-1997-3443, has been undertaken to distinguish illegal use of zeranol from consumption of food contaminated with Fusarium spp. toxin. One of the tasks was development of screening and confirmatory methods of analysis. This paper describ... |
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Cytosol protein regulation in H295R steroidogenesis model induced by the zearalenone metabolites, α- and β-zearalenol.
Toxicon 59(1) , 17-24, (2012) α- and β-zearalenol (α-ZOL and β-ZOL, respectively) are metabolites of the mycotoxin zearalenone (ZEN). All three individual mycotoxins have shown to be biological active i.e. being estrogenic and able to stimulate cellular proliferation albeit at different s... |
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Determination of the cross-reactivities for alpha-zearalenol, beta-zearalenol, zearalanone, alpha-zearalanol, and beta-zearalanol on three commercial immunoaffinity columns targeting zearalenone.
J. AOAC Int. 90(4) , 1197-202, (2007) Immunoaffinity extraction has become increasingly important as a sample preparation and cleanup method in mycotoxin analysis. In this study, the antibody specificities of 3 commercial immunoaffinity columns (IACs) targeting zearalenone (ZON) were compared for... |
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The activities of mycotoxins derived from Fusarium and related substances in a short-term transformation assay using v-Ha-ras-transfected BALB/3T3 cells (Bhas 42 cells).
Mutat. Res. 630(1-2) , 103-11, (2007) Cell transformation assays using BALB/3T3 cells can mimic the two-stage process of chemical carcinogenesis in experimental animals. A short-term transformation assay using v-Ha-ras-transfected BALB/3T3 cells (Bhas 42 cells), which was developed by Ohmori et a... |
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Hydroxysteroid dehydrogenases in bovine and porcine granulosa cells convert zearalenone into its hydroxylated metabolites alpha-zearalenol and beta-zearalenol.
Vet. Res. Commun. 30(4) , 445-53, (2006) The enzymes 3alpha- and 3beta-hydroxysteroid dehydrogenase (3alpha- and 3beta-HSD) play a pivotal role in synthesis of various steroid hormones including oestradiol and testosterone. The structure of the mycotoxin zearalenone resembles many characteristics of... |
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Glucuronidation of zearalenone, zeranol and four metabolites in vitro: formation of glucuronides by various microsomes and human UDP-glucuronosyltransferase isoforms.
Mol. Nutr. Food. Res. 54(10) , 1468-76, (2010) Glucuronidation constitutes an important pathway in the phase II metabolism of the mycotoxin zearalenone (ZEN) and the growth promotor α-zearalanol (α-ZAL, zeranol), but the enzymology of their formation is yet unknown. In the present study, ZEN, α-ZAL and fo... |
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Estrogenic potencies of resorcylic acid lactones and 17 beta-estradiol in female rats.
J. Toxicol. Environ. Health A 20(4) , 435-43, (1987) Uterotrophic response in sexually immature female rats has been used to rank the relative estrogenic potencies of six resorcylic acid lactones (RALs) and to compare their activities with that of 17 beta-estradiol. On oral administration, the estrogenic potenc... |
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Development of an analytical system for the simultaneous determination of anabolic macrocyclic lactones in aquatic environmental samples.
Rapid Commun. Mass Spectrom. 15(4) , 304-10, (2001) An analytical procedure that enables routine analysis for trace determination of six anabolic macrocyclic lactones (zearalenone, alpha- and beta-zearalenol, zearalanone, zeranol, and taleranol) in sewage treatment plant (STP) samples has been developed. The m... |
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Confirmatory assay for zeranol, taleranol and the Fusarium spp. toxins in bovine urine using liquid chromatography-tandem mass spectrometry.
Food Addit. Contam. 21(1) , 52-62, (2004) A method is described for the quantitative determination of the veterinary drug zeranol, its epimer taleranol and the mycotoxins zearalenone, alpha-zearalenol and beta-zearalenol in bovine urine. The method is based on liquid chromatography coupled to negativ... |
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Prevalence of zeranol, taleranol and Fusarium spp. toxins in urine: implications for the control of zeranol abuse in the European Union.
Food Addit. Contam. 21(9) , 833-9, (2004) There is currently little information concerning the prevalence of zeranol and taleranol in animal urine following metabolism of the naturally occurring Fusarium spp. toxins. An epidemiological study is described which involves four European Union control lab... |