PD 123319 二(三氟乙酸盐)
PD 123319 二(三氟乙酸盐)结构式
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常用名 | PD 123319 二(三氟乙酸盐) | 英文名 | PD123319 di(trifluoroacetate) |
|---|---|---|---|---|
| CAS号 | 136676-91-0 | 分子量 | 736.657 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C35H34F6N4O7 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
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Contractility of placental vascular smooth muscle cells in response to stimuli produced by the placenta: roles of ACE vs. non-ACE and AT1 vs. AT2 in placental vessel cells.
Placenta 29(6) , 503-9, (2008) Our previously published work has shown that non-ACE angiotensin II (Ang II) generating system is dominate in the placenta and may play a critical role in regulation of placental vascular contractile function. In the present study, using a collagen gel contra... |
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Modulation of angiotensin II binding affinity by allosteric interaction of polyvinyl sulfate with an intracellular domain of the DuP-753-sensitive angiotensin II receptor of bovine adrenal glomerulosa.
Mol. Pharmacol. 41 , 809-815, (1992) Angiotensin II (AII) is an important regulator of aldosterone secretion by adrenal glomerulosa cells. All interacts with a specific receptor coupled to a guanine nucleotide-binding protein that controls the activity of phospholipase C. Recently, novel All non... |
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Differential blockade of central effects of angiotensin II by AT2-receptor antagonists.
Am. J. Physiol. 265 , H226, (1993) In conscious, chronically instrumented, male Long-Evans rats, we showed previously that central administration (intracerebroventricular) of the AT1-receptor antagonist EXP-3174 (1 microgram) caused a rapid-onset marked, but transient, blockade of the regional... |
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Biochemical characterization of two distinct angiotensin AT2 receptor populations in murine neuroblastoma N1E-115 cells.
J. Neurochem. 62 , 2106-2115, (1994) The murine neuroblastoma N1E-115 cell line possesses a high density of angiotensin II (AngII) receptors that can be solubilized with the zwitterionic detergent 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate. These solubilized binding sites exhibite... |
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Developmental effect of antenatal exposure to betamethasone on renal angiotensin II activity in the young adult sheep.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 298 , F847-F856, (2010) Antenatal corticosteroids may have long-term effects on renal development which have not been clearly defined. Our objective was to compare the responses to intrarenal infusions of ANG II in two groups of year-old, male sheep: one group exposed to a clinicall... |