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糖肽酶 A 来源于杏仁

糖肽酶 A 来源于杏仁结构式
糖肽酶 A 来源于杏仁结构式
品牌特惠专场
常用名 糖肽酶 A 来源于杏仁 英文名 PNGase F
CAS号 83534-39-8 分子量 N/A
密度 N/A 沸点 N/A
分子式 N/A 熔点 N/A
MSDS 美版 闪点 N/A
符号 GHS05 GHS06 GHS09
GHS05, GHS06, GHS09
信号词 Danger

The characterization and quantitation of glycomic changes in CHO cells during a bioreactor campaign.

Biotechnol. Bioeng. 109(12) , 3007-17, (2012)

Within the biotechnology industry there is a continuous drive to better and more fully understand the biopharmaceutical process in order to achieve better process control. A method to monitor and quantitate glycomic changes that occur in CHO cells during a bi...

N-Terminal signal sequence is required for cellular trafficking and hyaluronan-depolymerization of KIAA1199.

FEBS Lett. 588(1) , 111-6, (2014)

Recently, we disclosed that KIAA1199-mediated hyaluronan (HA) depolymerization requires an acidic cellular microenvironment (e.g. clathrin-coated vesicles or early endosomes), but no information about the structural basis underlying the cellular targeting and...

Liver and muscle hemojuvelin are differently glycosylated.

BMC Biochem. 12 , 52, (2011)

Hemojuvelin (HJV) is one of essential components for expression of hepcidin, a hormone which regulates iron transport. HJV is mainly expressed in muscle and liver, and processing of HJV in both tissues is similar. However, hepcidin is expressed in liver but n...

Reversal of neuropathic pain in diabetes by targeting glycosylation of Ca(V)3.2 T-type calcium channels.

Diabetes 62(11) , 3828-38, (2013)

It has been established that Ca(V)3.2 T-type voltage-gated calcium channels (T-channels) play a key role in the sensitized (hyperexcitable) state of nociceptive sensory neurons (nociceptors) in response to hyperglycemia associated with diabetes, which in turn...

Effect of the GPI anchor of human Thy-1 on antibody recognition and function.

Lab. Invest. 93(3) , 365-74, (2013)

Thymocyte differentiation antigen-1 (Thy-1) is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein expressed on numerous cell types, which regulates signals affecting cell adhesion, migration, differentiation, and survival. In addition, Thy-...

LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins.

J. Proteome Res. 12(2) , 573-84, (2013)

The GalNAc O-glycosylation on Ser/Thr residues of extracellular proteins has not been well characterized from a proteomics perspective. We previously reported a sialic acid capture-and-release protocol to enrich tryptic N- and O-glycopeptides from human cereb...

In vivo deglycosylation of recombinant proteins in plants by co-expression with bacterial PNGase F.

Bioengineered 4(5) , 338-42, (2013)

At present, several eukaryotic expression systems including yeast, insect and mammalian cells and plants are used for the production of recombinant proteins. Proteins with potential N-glycosylation sites are efficiently glycosylated when expressed in these sy...

Avidity confers FcγR binding and immune effector function to aglycosylated immunoglobulin G1.

J. Mol. Recognit. 25(3) , 147-54, (2012)

Immunoglobulin G (IgG) antibodies are an integral part of the adaptive immune response that provide a direct link between humoral and cellular components of the immune system. Insights into relationships between the structure and function of human IgGs have p...

Some characteristics of a new glycopeptidase acting on aspartylglycosylamine linkages.

J. Biochem. 84(6) , 1467-73, (1978)

A new type of glycopeptidase hydrolyzing beta-aspartylglycosylamine linkages was partially purified from almond emulsin by chromatography on Sephadex G-200 and DE 52. The enzyme degraded stem bromelain glycopeptide, Asn-Asn(Man3,Xyl1,Fuc1,GlcNAc2)-Glu-Ser-Ser...

NMR characterization of the interaction between the PUB domain of peptide:N-glycanase and ubiquitin-like domain of HR23

FEBS Lett. 586(8) , 1141-6, (2012)

Highlights ► PUB domain of PNGase binds to HR23–UBL more preferentially than ubiquitin chains. ► 3D model of the PUB–UBL complex is presented based on NMR data. ► The PUB–UBL complex is mediated by electrostatic interactions. ► PUB binds the UBL surface invol...