1-甲基-1H-吡唑-5-羧酸
1-甲基-1H-吡唑-5-羧酸结构式
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常用名 | 1-甲基-1H-吡唑-5-羧酸 | 英文名 | 1-Methylpyrazole-5-carboxylic Acid |
|---|---|---|---|---|
| CAS号 | 16034-46-1 | 分子量 | 126.11 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 306.9±15.0 °C at 760 mmHg | |
| 分子式 | C5H6N2O2 | 熔点 | 223.5-224.5 | |
| MSDS | 中文版 美版 | 闪点 | 139.4±20.4 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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The aryl hydrocarbon receptor suppresses osteoblast proliferation and differentiation through the activation of the ERK signaling pathway.
Toxicol. Appl. Pharmacol. 280(3) , 502-10, (2014) Ahr activation is known to be associated with synovitis and exacerbated rheumatoid arthritis (RA), but its contributions to bone loss have not been completely elucidated. Osteoblast proliferation and differentiation are abnormal at the erosion site in RA. Her... |
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Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish.
Aquat. Toxicol. 154 , 71-9, (2014) Firemaster 550 (FM550) is an additive flame retardant mixture used within polyurethane foam and is increasingly found in house dust and the environment due to leaching. Despite the widespread use of FM550, very few studies have investigated the potential toxi... |
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