1-Methylpyrazole-5-carboxylic Acid
1-Methylpyrazole-5-carboxylic Acid structure
|
Common Name | 1-Methylpyrazole-5-carboxylic Acid | ||
|---|---|---|---|---|
| CAS Number | 16034-46-1 | Molecular Weight | 126.11 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 306.9±15.0 °C at 760 mmHg | |
| Molecular Formula | C5H6N2O2 | Melting Point | 223.5-224.5 | |
| MSDS | Chinese USA | Flash Point | 139.4±20.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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The aryl hydrocarbon receptor suppresses osteoblast proliferation and differentiation through the activation of the ERK signaling pathway.
Toxicol. Appl. Pharmacol. 280(3) , 502-10, (2014) Ahr activation is known to be associated with synovitis and exacerbated rheumatoid arthritis (RA), but its contributions to bone loss have not been completely elucidated. Osteoblast proliferation and differentiation are abnormal at the erosion site in RA. Her... |
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Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish.
Aquat. Toxicol. 154 , 71-9, (2014) Firemaster 550 (FM550) is an additive flame retardant mixture used within polyurethane foam and is increasingly found in house dust and the environment due to leaching. Despite the widespread use of FM550, very few studies have investigated the potential toxi... |
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