Ro 90-7501
Ro 90-7501结构式
|
常用名 | Ro 90-7501 | 英文名 | Ro 90-7501 |
|---|---|---|---|---|
| CAS号 | 293762-45-5 | 分子量 | 340.38100 | |
| 密度 | 1.443g/cm3 | 沸点 | 751.035ºC at 760 mmHg | |
| 分子式 | C20H16N6 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 449.122ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Self-assembly of beta-amyloid 42 is retarded by small molecular ligands at the stage of structural intermediates.
J. Struct. Biol. 130 , 232-246, (2000) Assemblyof the amyloid-beta peptide (Abeta) into fibrils and its deposition in distinct brain areas is considered responsible for the pathogenesis of Alzheimer's disease (AD). Thus, inhibition of fibril assembly is a potential strategy for therapeutic interve... |
|
|
Protein aggregation and neurodegenerative disease.
Nat. Med. 10 Suppl , S10-S17 , (2004) Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), amyotrophic lateral sclerosis (ALS) and prion diseases are increasingly being realized to have common cellular and molecular mechanisms including... |
期刊文献综述：
更多...