Ro 90-7501
Ro 90-7501 structure
|
Common Name | Ro 90-7501 | ||
|---|---|---|---|---|
| CAS Number | 293762-45-5 | Molecular Weight | 340.38100 | |
| Density | 1.443g/cm3 | Boiling Point | 751.035ºC at 760 mmHg | |
| Molecular Formula | C20H16N6 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 449.122ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Self-assembly of beta-amyloid 42 is retarded by small molecular ligands at the stage of structural intermediates.
J. Struct. Biol. 130 , 232-246, (2000) Assemblyof the amyloid-beta peptide (Abeta) into fibrils and its deposition in distinct brain areas is considered responsible for the pathogenesis of Alzheimer's disease (AD). Thus, inhibition of fibril assembly is a potential strategy for therapeutic interve... |
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Protein aggregation and neurodegenerative disease.
Nat. Med. 10 Suppl , S10-S17 , (2004) Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), amyotrophic lateral sclerosis (ALS) and prion diseases are increasingly being realized to have common cellular and molecular mechanisms including... |
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