替可克肽
替可克肽结构式
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常用名 | 替可克肽 | 英文名 | Adrenocorticotropic Hormone Fragment 1-24 human |
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| CAS号 | 16960-16-0 | 分子量 | 2933.437 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | N/A | |
| 分子式 | C136H210N40O31S | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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An LC-MS/MS method for steroid profiling during adrenal venous sampling for investigation of primary aldosteronism.
J. Steroid Biochem. Mol. Biol. 145 , 75-84, (2015) Steroid profiling for diagnosis of endocrine disorders featuring disordered production of steroid hormones is now possible from advances in liquid chromatography with tandem mass spectrometry (LC-MS/MS). Adrenal venous (AV) measurements of aldosterone and cor... |
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The relationship between vitamin D status and adrenal insufficiency in critically ill children.
J. Clin. Endocrinol. Metab. 98(5) , E877-81, (2013) Recent studies in critically ill populations have suggested both adrenal insufficiency (AI) and vitamin D deficiency to be associated with worse clinical outcome. There are multiple mechanisms through which these pleiotropic hormones might synergistically inf... |
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Free and total plasma cortisol measured by immunoassay and mass spectrometry following ACTH₁₋₂₄ stimulation in the assessment of pituitary patients.
J. Clin. Endocrinol. Metab. 98(5) , 1883-90, (2013) Measurement of plasma cortisol by immunoassay after ACTH₁₋₂₄ stimulation is used to assess the hypothalamic-pituitary-adrenal (HPA) axis. Liquid chromatography-tandem mass spectrometry (LCMS) has greater analytical specificity than immunoassay and equilibrium... |
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Comparison of IV and IM formulations of synthetic ACTH for ACTH stimulation tests in healthy dogs.
J. Vet. Intern. Med. 26(2) , 412-4, (2012) Two commercially available forms of synthetic ACTH are used to diagnose and monitor hyper- and hypoadrenocorticism in dogs.To compare the biologic activity of the liquid and lyophilized forms of cosyntropin.Eighteen privately owned healthy dogs were included.... |
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Estimation of maximal cortisol secretion rate in healthy humans.
J. Clin. Endocrinol. Metab. 97(4) , 1285-93, (2012) Cortisol secretion is related to ACTH concentration by a sigmoidal dose-response curve, in which high ACTH concentrations drive maximal cortisol secretion rates (CSR(max)).We sought to estimate CSR(max) and free cortisol half-life in healthy humans (n = 21) u... |
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The short Synacthen test: a questionnaire survey of current usage.
Arch. Dis. Child. 97(10) , 870-3, (2012) Supported by meta-analyses, the low-dose Synacthen test (LDST) has gained in popularity, with many believing it to be more sensitive than the supraphysiological standard (250 µg) short ST (SSST), particularly when assessing children prescribed high-dose inhal... |
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The diagnostic value of first-voided urinary LH compared with GNRH-stimulated gonadotropins in differentiating slowly progressive from rapidly progressive precocious puberty in girls.
Eur. J. Endocrinol. 170(5) , 749-58, (2014) Characterization of pubertal progression is required to prevent unnecessary intervention in unsustained or slowly progressive (SP) precocious puberty (PP), while delivering hormonal suppression in rapidly progressive (RP) PP. We aimed to assess the diagnostic... |
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Cortisol response to synacthen stimulation is attenuated following abusive head trauma.
Clin. Endocrinol. (Oxf.) 77(3) , 357-62, (2012) Child abuse and other early-life environmental stressors are known to affect the hypothalamic-pituitary-adrenal axis. We sought to compare synacthen-stimulated cortisol responses in children who suffered inflicted or accidental traumatic brain injury (TBI).Ch... |
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Evaluation of serum concentrations of cortisol and sex hormones of adrenal gland origin after stimulation with two synthetic ACTH preparations in clinically normal dogs.
Am. J. Vet. Res. 73(2) , 237-41, (2012) To compare the adrenocortical response of healthy dogs to a commonly used dose of a nonadsorbed tetracosactide product (tetracosactide) with responses to 2 doses of a depot formulation of tetracosactide (depot tetracosactide).14 dogs.Dogs were randomly assign... |
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US practitioner opinions and prescribing practices regarding corticosteroid therapy for severe sepsis and septic shock.
J. Crit. Care 27(4) , 351-61, (2012) The aim of this study was to examine opinions and practices of US critical care practitioners (USCCPs) toward corticosteroid therapy in adult patients with severe sepsis or septic shock.A multicenter, electronic survey of USCCP members of the Society of Criti... |