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N-乙酰半胱氨酸酰胺

N-乙酰半胱氨酸酰胺结构式
N-乙酰半胱氨酸酰胺结构式
品牌特惠专场
常用名 N-乙酰半胱氨酸酰胺 英文名 N-Acetylcysteine amide
CAS号 38520-57-9 分子量 162.21000
密度 N/A 沸点 N/A
分子式 C5H10N2O2S 熔点 N/A
MSDS 中文版 美版 闪点 N/A
符号 GHS07
GHS07
信号词 Warning

Gambogic acid sensitizes resistant breast cancer cells to doxorubicin through inhibiting P-glycoprotein and suppressing survivin expression.

Chem. Biol. Interact. 235 , 76-84, (2015)

The development of resistance to chemotherapeutic agents remains a major challenge to breast cancer chemotherapy. Overexpression of drug efflux transporters like P-glycoprotein (P-gp) and resistance to apoptosis are the two key factors that confer cancer drug...

Atmospheric gas plasma-induced ROS production activates TNF-ASK1 pathway for the induction of melanoma cancer cell apoptosis.

Mol. Biol. Cell 25(9) , 1523-31, (2014)

Atmospheric gas plasmas (AGPs) are able to selectively induce apoptosis in cancer cells, offering a promising alternative to conventional therapies that have unwanted side effects such as drug resistance and toxicity. However, the mechanism of AGP-induced can...

Mutations in the mitochondrial methionyl-tRNA synthetase cause a neurodegenerative phenotype in flies and a recessive ataxia (ARSAL) in humans.

PLoS Biol. 10 , e1001288, (2012)

An increasing number of genes required for mitochondrial biogenesis, dynamics, or function have been found to be mutated in metabolic disorders and neurological diseases such as Leigh Syndrome. In a forward genetic screen to identify genes required for neuron...

Oxidative stress and lipid peroxidation are upstream of amyloid pathology.

Neurobiol. Dis. 84 , 109-19, (2015)

Oxidative stress is a common feature of the aging process and of many neurodegenerative disorders, including Alzheimer's disease. Understanding the direct causative relationship between oxidative stress and amyloid pathology, and determining the underlying mo...

Atmospheric pressure gas plasma-induced colorectal cancer cell death is mediated by Nox2-ASK1 apoptosis pathways and oxidative stress is mitigated by Srx-Nrf2 anti-oxidant system.

Biochim. Biophys. Acta 1843(12) , 2827-37, (2014)

Atmospheric pressure gas plasma (AGP) generates reactive oxygen species (ROS) that induce apoptosis in cultured cancer cells. The majority of cancer cells develop a ROS-scavenging anti-oxidant system regulated by Nrf2, which confers resistance to ROS-mediated...