甲醇(6 -乙酰吗啡)
甲醇(6 -乙酰吗啡)结构式
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常用名 | 甲醇(6 -乙酰吗啡) | 英文名 | 6-acetylmorphine |
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| CAS号 | 2784-73-8 | 分子量 | 327.37400 | |
| 密度 | 1.38g/cm3 | 沸点 | 470.2ºC at 760mmHg | |
| 分子式 | C19H21NO4 | 熔点 | 184-189ºC | |
| MSDS | N/A | 闪点 | 238.2ºC | |
| 符号 |
GHS02, GHS06 |
信号词 | Danger |
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Dynamic vaccine blocks relapse to compulsive intake of heroin.
Proc. Natl. Acad. Sci. U. S. A. 110(22) , 9036-41, (2013) Heroin addiction, a chronic relapsing disorder characterized by excessive drug taking and seeking, requires constant psychotherapeutic and pharmacotherapeutic interventions to minimize the potential for further abuse. Vaccine strategies against many drugs of ... |
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Validation of a gas chromatography-ion trap-tandem mass spectrometry assay for the simultaneous quantification of cocaine, benzoylecgonine, cocaethylene, morphine, codeine, and 6-acetylmorphine in aqueous solution, blood, and skeletal muscle tissue.
J. Anal. Toxicol. 36(1) , 1-11, (2012) A gas chromatography-ion trap-tandem mass spectrometry method was developed and validated for the simultaneous solid-phase extraction and quantification of cocaine, benzoylecgonine, cocaethylene, morphine, codeine, and 6-monoacteylmorphine in blood, muscle ti... |
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Simultaneous determination of xylazine, free morphine, codeine, 6-acetylmorphine, cocaine and benzoylecgonine in postmortem blood by UPLC-MS-MS.
J. Anal. Toxicol. 36(5) , 319-26, (2012) Xylazine, a veterinary sedative, has been found as an adulterant of heroin in street drugs in Puerto Rico. It was found in combination with free morphine and 6-acetylmorphine, codeine, cocaine and benzoylecgonine in postmortem cases at the Puerto Rico Institu... |
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Analytical evaluation of four on-site oral fluid drug testing devices.
J. Anal. Toxicol. 36(2) , 136-40, (2012) The use of oral fluid (OF) as an alternative matrix for the detection of drugs of abuse has increased over the last decade, leading to the need for a rapid, simple, and reliable on-site OF testing device. Four on-site OF drug testing devices (Dräger DrugTest ... |
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Detection of drugs of abuse in exhaled breath from users following recovery from intoxication.
J. Anal. Toxicol. 36(9) , 638-46, (2012) It has recently been demonstrated that amphetamine, methadone and tetrahydrocannabinol are detectable in exhaled breath following intake. Exhaled breath, therefore, constitutes a new possible matrix for drugs-of-abuse testing. The present work aims to further... |
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Drugs of abuse and benzodiazepines in the Madrid Region (Central Spain): seasonal variation in river waters, occurrence in tap water and potential environmental and human risk.
Environ. Int. 70 , 76-87, (2014) This work analyzes the seasonal variation (winter and summer) of ten drugs of abuse, six metabolites and three benzodiazepines in surface waters from the Jarama and Manzanares Rivers in the Madrid Region, the most densely populated area in Spain. The occurren... |
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Selective effects of a morphine conjugate vaccine on heroin and metabolite distribution and heroin-induced behaviors in rats.
J. Pharmacol. Exp. Ther. 344(2) , 397-406, (2013) Morphine conjugate vaccines have effectively reduced behavioral effects of heroin in rodents and primates. To better understand how these effects are mediated, heroin and metabolite distribution studies were performed in rats in the presence and absence of va... |
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Quantitation of opioids in whole blood by electron impact-gas chromatography-mass spectrometry.
J. Anal. Toxicol. 35(2) , 99-107, (2011) Opioids are frequently encountered in Forensic Toxicology casework. A PubMed literature search was conducted to find a method using electron impact-gas chromatography-mass spectrometry to examine whole blood specimens. A previously published method was identi... |
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Determination of opiates in whole blood and vitreous humor: a study of the matrix effect and an experimental design to optimize conditions for the enzymatic hydrolysis of glucuronides.
J. Anal. Toxicol. 36(3) , 162-70, (2012) Undoubtedly, whole blood and vitreous humor have been biological samples of great importance in forensic toxicology. The determination of opiates and their metabolites has been essential for better interpretation of toxicological findings. This report describ... |
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2-Nitro-6-monoacetylmorphine: potential marker for monitoring the presence of 6-monoacetylmorphine in urine adulterated with potassium nitrite.
Anal. Bioanal. Chem 403(7) , 2057-63, (2012) 6-Monoacetylmorphine (6-MAM), being a unique metabolite of heroin, is routinely tested in urine samples to monitor heroin use. However, detection of 6-MAM-related opiates such as morphine is known to be affected by in vitro urine adulteration using oxidizing ... |