6-acetylmorphine

Modify Date: 2024-01-02 17:15:11

6-acetylmorphine Structure
6-acetylmorphine structure
Common Name 6-acetylmorphine
CAS Number 2784-73-8 Molecular Weight 327.37400
Density 1.38g/cm3 Boiling Point 470.2ºC at 760mmHg
Molecular Formula C19H21NO4 Melting Point 184-189ºC
MSDS N/A Flash Point 238.2ºC
Symbol GHS02 GHS06
GHS02, GHS06
Signal Word Danger

 Names

Name 6-Acetyl Morphine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.38g/cm3
Boiling Point 470.2ºC at 760mmHg
Melting Point 184-189ºC
Molecular Formula C19H21NO4
Molecular Weight 327.37400
Flash Point 238.2ºC
Exact Mass 327.14700
PSA 59.00000
LogP 1.70680
Vapour Pressure 1.83E-09mmHg at 25°C
Index of Refraction 1.665

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QC7814500
CHEMICAL NAME :
Morphinan-3,6-alpha-diol, 7,8-didehydro-4,5-alpha-epoxy-17-methyl-, 6-acetate
CAS REGISTRY NUMBER :
2784-73-8
LAST UPDATED :
199512
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H21-N-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
59 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJPHAZ European Journal of Pharmacology. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1967- Volume(issue)/page/year: 85,317,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intracerebral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
147 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJPHAZ European Journal of Pharmacology. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1967- Volume(issue)/page/year: 85,317,1982

 Safety Information

Symbol GHS02 GHS06
GHS02, GHS06
Signal Word Danger
Hazard Statements H225-H302 + H312-H319-H331
Precautionary Statements P210-P261-P280-P305 + P351 + P338-P311
Hazard Codes F: Flammable;Xn: Harmful;
Risk Phrases 11-20/21/22-36
Safety Phrases 16-36/37-26
RIDADR UN 1648 3/PG 2

 Articles26

More Articles
Dynamic vaccine blocks relapse to compulsive intake of heroin.

Proc. Natl. Acad. Sci. U. S. A. 110(22) , 9036-41, (2013)

Heroin addiction, a chronic relapsing disorder characterized by excessive drug taking and seeking, requires constant psychotherapeutic and pharmacotherapeutic interventions to minimize the potential f...

Validation of a gas chromatography-ion trap-tandem mass spectrometry assay for the simultaneous quantification of cocaine, benzoylecgonine, cocaethylene, morphine, codeine, and 6-acetylmorphine in aqueous solution, blood, and skeletal muscle tissue.

J. Anal. Toxicol. 36(1) , 1-11, (2012)

A gas chromatography-ion trap-tandem mass spectrometry method was developed and validated for the simultaneous solid-phase extraction and quantification of cocaine, benzoylecgonine, cocaethylene, morp...

Simultaneous determination of xylazine, free morphine, codeine, 6-acetylmorphine, cocaine and benzoylecgonine in postmortem blood by UPLC-MS-MS.

J. Anal. Toxicol. 36(5) , 319-26, (2012)

Xylazine, a veterinary sedative, has been found as an adulterant of heroin in street drugs in Puerto Rico. It was found in combination with free morphine and 6-acetylmorphine, codeine, cocaine and ben...

 Synonyms

[(4R,4aR,7S,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl] acetate