4-哌啶丁酸盐酸盐
4-哌啶丁酸盐酸盐结构式
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常用名 | 4-哌啶丁酸盐酸盐 | 英文名 | 4-(Piperidin-4-yl)butanoic acid hydrochloride |
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| CAS号 | 84512-08-3 | 分子量 | 207.698 | |
| 密度 | N/A | 沸点 | 344.3ºC at 760 mmHg | |
| 分子式 | C9H18ClNO2 | 熔点 | 113-117ºC(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 99ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Synthesis and biological evaluation of isosteric analogues of FK866, an inhibitor of NAD salvage.
ChemMedChem 3 , 771-779, (2008) One of the great challenges of medicinal chemistry is to create novel, effective, chemotherapeutic agents that show specificity for cancer cells combined with low systemic toxicity. A novel idea is to target the enzymes of the NAD biosynthesis and recycling p... |
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Design, synthesis and X-ray crystallographic study of NAmPRTase inhibitors as anti-cancer agents.
Eur. J. Med. Chem. 46 , 1153-1164, (2011) NAmPRTase (PBEF/Visfatin) plays a pivotal role in the salvage pathway of NAD(+) biosynthesis. NAmPRTase has been an attractive target for anti-cancer agents that induce apoptosis of tumor cells via a declining plasma NAD(+) level. In this report, a series of ... |
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Characterization of NAD uptake in mammalian cells. Billington RA, et al.
J. Biol. Chem. 283(10) , 6367-6374, (2008)
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