4-(Piperidin-4-yl)butanoic acid hydrochloride
4-(Piperidin-4-yl)butanoic acid hydrochloride structure
|
Common Name | 4-(Piperidin-4-yl)butanoic acid hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 84512-08-3 | Molecular Weight | 207.698 | |
| Density | N/A | Boiling Point | 344.3ºC at 760 mmHg | |
| Molecular Formula | C9H18ClNO2 | Melting Point | 113-117ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 99ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Synthesis and biological evaluation of isosteric analogues of FK866, an inhibitor of NAD salvage.
ChemMedChem 3 , 771-779, (2008) One of the great challenges of medicinal chemistry is to create novel, effective, chemotherapeutic agents that show specificity for cancer cells combined with low systemic toxicity. A novel idea is to target the enzymes of the NAD biosynthesis and recycling p... |
|
|
Design, synthesis and X-ray crystallographic study of NAmPRTase inhibitors as anti-cancer agents.
Eur. J. Med. Chem. 46 , 1153-1164, (2011) NAmPRTase (PBEF/Visfatin) plays a pivotal role in the salvage pathway of NAD(+) biosynthesis. NAmPRTase has been an attractive target for anti-cancer agents that induce apoptosis of tumor cells via a declining plasma NAD(+) level. In this report, a series of ... |
|
|
Characterization of NAD uptake in mammalian cells. Billington RA, et al.
J. Biol. Chem. 283(10) , 6367-6374, (2008)
|