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3,3′-二庚基氧化碳菁碘化物

3,3′-二庚基氧化碳菁碘化物结构式
3,3′-二庚基氧化碳菁碘化物结构式
品牌特惠专场
常用名 3,3′-二庚基氧化碳菁碘化物 英文名 DiOC7(3)
CAS号 53213-83-5 分子量 600.57400
密度 N/A 沸点 N/A
分子式 C31H41IN2O2 熔点 N/A
MSDS 中文版 美版 闪点 N/A
符号 GHS07 GHS08
GHS07, GHS08
信号词 Danger

Tissue penetration and activity of camptothecins in solid tumor xenografts.

Mol. Cancer Ther. 13(11) , 2727-37, (2014)

The ability of a panel of camptothecin derivatives to access the tumor compartment was evaluated to determine the mechanisms by which the architecture of solid tumors may act to limit their activity. Microregional localization and activity of members of the c...

Use of a carbocyanine dye as a marker of functional vasculature in murine tumours.

Br. J. Cancer 59 , 706, (1989)

An intravenously administered fluorescent carbocyanine dye, DiOC7(3), has been evaluated for use in conjunction with Hoechst 33342 as a marker of murine tumour vasculature. DiOC7(3) stains cells immediately adjacent to blood vessels and thus, like Hoechst 333...

Pontentiometric cyanine dyes are sensitive probes for mitochondria in intact plant cells : kinetin enhances mitochondrial fluorescence.

Plant Physiol. 84 , 1385, (1987)

Selected fluorescent dyes were tested for uptake by mitochrondria in intact cells of barley, maize, and onion. The cationic cyanine dye 3,3'-diheptyloxacarbocyanine iodide [DiOC(7)(3)] accumulated in mitochondria within 15 to 30 minutes without appreciable st...

Targeting the tumour vasculature: exploitation of low oxygenation and sensitivity to NOS inhibition by treatment with a hypoxic cytotoxin.

PLoS ONE 8 , e76832, (2013)

Many cancer research efforts focus on exploiting genetic-level features that may be targeted for therapy. Tissue-level features of the tumour microenvironment also represent useful therapeutic targets. Here we investigate the presence of low oxygen tension an...