DiOC7(3)
DiOC7(3) structure
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Common Name | DiOC7(3) | ||
|---|---|---|---|---|
| CAS Number | 53213-83-5 | Molecular Weight | 600.57400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C31H41IN2O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
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Tissue penetration and activity of camptothecins in solid tumor xenografts.
Mol. Cancer Ther. 13(11) , 2727-37, (2014) The ability of a panel of camptothecin derivatives to access the tumor compartment was evaluated to determine the mechanisms by which the architecture of solid tumors may act to limit their activity. Microregional localization and activity of members of the c... |
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Use of a carbocyanine dye as a marker of functional vasculature in murine tumours.
Br. J. Cancer 59 , 706, (1989) An intravenously administered fluorescent carbocyanine dye, DiOC7(3), has been evaluated for use in conjunction with Hoechst 33342 as a marker of murine tumour vasculature. DiOC7(3) stains cells immediately adjacent to blood vessels and thus, like Hoechst 333... |
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Pontentiometric cyanine dyes are sensitive probes for mitochondria in intact plant cells : kinetin enhances mitochondrial fluorescence.
Plant Physiol. 84 , 1385, (1987) Selected fluorescent dyes were tested for uptake by mitochrondria in intact cells of barley, maize, and onion. The cationic cyanine dye 3,3'-diheptyloxacarbocyanine iodide [DiOC(7)(3)] accumulated in mitochondria within 15 to 30 minutes without appreciable st... |
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Targeting the tumour vasculature: exploitation of low oxygenation and sensitivity to NOS inhibition by treatment with a hypoxic cytotoxin.
PLoS ONE 8 , e76832, (2013) Many cancer research efforts focus on exploiting genetic-level features that may be targeted for therapy. Tissue-level features of the tumour microenvironment also represent useful therapeutic targets. Here we investigate the presence of low oxygen tension an... |